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- Title
An Efficient Solventless Method for the Synthesis of N,N-Dialkyl Sulfonamide Derivatives.
- Authors
Zare, A.; Hasaninejad, A.; Zare, A. R. Moosavi; Khalafi-Nezhad, A.; Parhami, A.
- Abstract
Aza-Michael addition of sulfonamides to α,β-unsaturated esters efficiently proceeds in the presence of catalytic amount of sodium hydroxide (NaOH) and tetrabutylammonium bromide (TBAB) as a phase-transfer catalyst (PTC) under microwave irradiation to afford N,N-dialkyl sulfonamides as biologically interesting compounds in good to excellent yields and short reaction times.
- Subjects
BROMIDES; REACTION time; SULFONAMIDES; SODIUM hydroxide; CHEMICAL reactions; CHEMISTRY education; PHASE-transfer catalysis
- Publication
Journal of the Iranian Chemical Society, 2008, Vol 5, Issue 4, p617
- ISSN
1735-207X
- Publication type
Article
- DOI
10.1007/BF03246142