We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Chemical and biological investigations of Dillenia indica Linn.
- Authors
Parvin, Most. Nazma; Rahman, Mohammad S.; Islam, Mohammad S.; Rashid, Mohammad A.
- Abstract
A total of four compounds namely, lupeol (1), betulinaldehyde (2), betulinic acid (3) and stigmasterol (4) were isolated from the stem extract of Dillenia indica Linn. The structures of the isolated compounds (1-4) were established by extensive spectroscopic studies. The crude methanolic extracts and its n-hexane, carbon tetrachloride, dichloromethane and chloroform soluble partitionates demonstrated weak antimicrobial activity against a wide range of Grampositive and Gram-negative bacteria and fungi. The extractives revealed significant cytotoxic activity when tested by brine shrimp lethality bioassay. In addition, the extractives exhibited significant free radical scavenging activity when compared with ascorbic acid.
- Subjects
DILLENIACEAE; PLANT extracts; METHANOL; CARBON tetrachloride; DICHLOROMETHANE; CHLOROFORM; BIOLOGICAL assay
- Publication
Bangladesh Journal of Pharmacology, 2009, Vol 4, Issue 2, p122
- ISSN
1991-007X
- Publication type
Article
- DOI
10.3329/bjp.v4i2.2758