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- Title
Outcome of children with sickle cell disease admitted to intensive care – a single institution experience.
- Authors
Bartram, Jack L.; Thein, Swee L.; Gardner, Kate; Egberongbe, Yaya; D'Silva, Pam; Height, Susan E.; Dick, Moira C.; O'Driscoll, Sandra; Rees, David C.
- Abstract
We retrospectively audited children with sickle cell disease (SCD) admitted to paediatric intensive care (PICU) at King’s College Hospital between January 2000 and December 2008. Forty-six children with SCD were admitted, on 49 separate occasions. Ages ranged from 4 months to 15 years (median 7·6 years). Three children died in PICU, however two presented to hospital in cardiorespiratory arrest; overall mortality was 6%. The most common reason for admission was acute chest syndrome (43%). 88% of admissions required blood transfusion, of which 74% had exchange blood transfusions. The mortality among children with SCD admitted to PICU is low.
- Subjects
SICKLE cell anemia in children; PEDIATRIC intensive care; KING'S College Hospital PLC; BLOOD transfusion; BLOOD diseases; CARDIOPULMONARY system; DISEASES; GENETICS
- Publication
British Journal of Haematology, 2010, Vol 150, Issue 5, p614
- ISSN
0007-1048
- Publication type
Article
- DOI
10.1111/j.1365-2141.2010.08272.x