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- Title
Randomized controlled trial on treatment of bronchial asthma of qi-deficiency cold syndrome type by Pingchuan Yiqi Granule.
- Authors
Zhang Y; Chang J; Chi H; Mao B; Tang W; Wang L; Huang S; Li T; Zhang R; Tao B
- Abstract
Objective: To evaluate the effect and safety of Pingchuan Yiqi Granule ([Please see original document for Chinese characters] PYG) in treating bronchial asthma of qi-deficiency cold syndrome type (BS-QDC). Methods: With the randomized, positive agent parallel controlled design adopted, the 80 subjects enrolled were assigned in the ratio of 3:1 to two groups, the 60 patients in the trial group were treated with PYG and the 20 in the control group treated with Ruyi Dingchuan Pill ([Please see original document for Chinese characters] RDP), with the therapeutic course consisting of 7 days for both groups. The clinical effects, effects on TCM syndrome and the changes of lung function after treatment were observed. Results: The effect of the treatment on asthma in the trial group: clinically controlled rate was 6.67%, markedly effective rate 51.67%, improved rate 33.33% and ineffective rate 8.33%; and the corresponding rates in the control group were 5.00%, 50.00%, 30.00%, and 15.00% respectively. Comparison between the two groups showed insignificant difference (P>0.05). The effect on TCM syndrome in the treated group: clinically controlled rate was 11.67%, markedly effective rate 58.33%, effective rate 21.67% and ineffective rate 8.33%; and those in the control group were 10.00%, 50.00%, 30.00% and 10.00% respectively, also showing insignificant difference between the two groups (P>0.05). Lung function test showed that the change on forced expiratory volume in 1 second (FEV1) after treatment in the trial group was of statistical significance (P<0.05), but no significant difference was shown in the change of peak expiratory flow (PEF, P>0.05); while the changes in the control group were just the opposite, showing insignificance in FEV1 (P>0.05) but significance in PEF (P<0.05). Comparison of the therapeutic effect on lung function between the two groups showed no significant difference (P>0.05). No adverse reaction was found in either group in the course of treatment. Conclusion: PYG used to treat BS-QDC is effective and safe, it's effect is similar to that of RDP.
- Publication
Chinese Journal of Integrative Medicine, 2007, Vol 13, Issue 1, p27
- ISSN
1672-0415
- Publication type
Journal Article
- DOI
10.1007/s11655-007-0027-7