We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Mechanically Modulating the Photophysical Properties of Fluorescent Protein Biocomposites for Ratio- and Intensiometric Sensors.
- Authors
Brantley, Johnathan N.; Bailey, Constance B.; Cannon, Joe R.; Clark, Katie A.; Vanden Bout, David A.; Brodbelt, Jennifer S.; Keatinge-Clay, Adrian T.; Bielawski, Christopher W.
- Abstract
Mechanically sensitive biocomposites comprised of fluorescent proteins report stress through distinct pathways. Whereas a composite containing an enhanced yellow fluorescent protein (eYFP) exhibited hypsochromic shifts in its fluorescence emission maxima following compression, a composite containing a modified green fluorescent protein (GFPuv) exhibited fluorescence quenching under the action of mechanical force. These ratio- and intensiometric sensors demonstrate that insights garnered from disparate fields (that is, polymer mechanochemistry and biophysics) can be harnessed to guide the rational design of new classes of biomechanophore-containing materials.
- Subjects
YELLOW fluorescent protein; GREEN fluorescent protein; DETECTORS; BIOPHYSICS; FLUORESCENT polymers; METHYL methacrylate; QUENCHING (Chemistry)
- Publication
Angewandte Chemie, 2014, Vol 126, Issue 20, p5188
- ISSN
0044-8249
- Publication type
Article
- DOI
10.1002/ange.201306988