We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Seasonal Variation Influences on Intestinal Microbiota in Rats.
- Authors
Liu, Jie; Song, Yi; Lu, Xiaoguang; Chen, Tuo; Guo, Wenxiu; Fan, Zhiwei; Kang, Xin; Wang, Yu; Wang, Yi
- Abstract
Recently, several studies have indicated that the intestinal microbiota can be regulated by the individual attributes, and even the alternation of circadian rhythm. Inspired by this, we speculated that seasonal variation might also have some effect on the intestinal microbiota. A total of 11 Sprague-Dawley male rats, weighing 250-280 g, were divided into summer group (n = 5) and winter group (n = 6). Cages were individually ventilated at 20 ± 2 °C and 45-65% relative humidity with a circadian rhythm of 12/12 h. After 1 week of adaptively feeding, mucosal contents of jejunum, terminal ileum, and ascending colon were collected and analyzed by 16S rRNA Gene Amplicon Pyrosequencing. The results showed that intestinal microbiota of rats for the same strain were affected by season change under the same feeding condition and living environment. We should take seasonal factor into account in the future experimental design based on intestinal microbiome.
- Subjects
GUT microbiome; CIRCADIAN rhythms in animals; SPRAGUE Dawley rats; SEASONAL physiological variations; ANIMAL feeding behavior; PHYSIOLOGY
- Publication
Current Microbiology, 2018, Vol 75, Issue 8, p1006
- ISSN
0343-8651
- Publication type
Article
- DOI
10.1007/s00284-018-1480-6