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- Title
Vitamin C Status of US Adults Assessed as Part of the National Health and Nutrition Examination Survey Remained Unchanged between 2003–2006 and 2017–2018.
- Authors
Powers, Carissa D; Sternberg, Maya R; Patel, Sweta B; Pfeiffer, Christine M; Storandt, Renee J; Schleicher, Rosemary L
- Abstract
Background: We compared serum vitamin C (VIC) status of the adult (≥20 y) US population in the National Health and Nutrition Examination Survey (NHANES) 2017–2018 with combined data from 2003–2004 and 2005–2006. Methods: VIC was measured using HPLC with electrochemical detection. Mean data were stratified by age, sex, race/Hispanic origin, income, body mass index, dietary intake, supplement use, and smoking status. Prevalence of VIC deficiency (<11.4 μmol/L) was calculated. Results: In NHANES 2017–2018, the mean VIC was 8 μmol/L higher in people ≥60 y compared with those 20–59 y of age, 10 μmol/L lower in men vs women, 8 μmol/L lower in low vs high income, 11 μmol/L lower in obese vs healthy weight, and 15 μmol/L lower in smokers vs nonsmokers. Differences in mean VIC across race/Hispanic origin groups ranged from 2 to 7 μmol/L. Mean VIC was 27 μmol/L higher with vitamin C-containing supplement use and positively associated (Spearman ρ = 0.33; P < 0.0001) with increasing dietary intake. The associations between mean VIC and the investigated covariates were generally consistent and the prevalence of deficiency was not significantly different between survey periods (6.8% vs 7.0%; P = 0.83). However, a few subgroups had double the risk. We found no significant survey differences in mean VIC (51.2 vs 54.0 μmol/L; P = 0.09). Conclusions: Overall VIC status of the US adult population has remained stable since last assessed in the NHANES 2005–2006 survey. Vitamin C deficiency remained high for those with low dietary intake and who smoke.
- Subjects
VITAMIN C; HEALTH &; Nutrition Examination Survey; VITAMIN C deficiency; FOOD consumption; RACE; ADULTS
- Publication
Journal of Applied Laboratory Medicine, 2023, Vol 8, Issue 2, p272
- ISSN
2475-7241
- Publication type
Article
- DOI
10.1093/jalm/jfac093