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- Title
Successful debulking of plurihormonal pituitary macroadenoma with long‐acting pasireotide and dopamine agonist combination therapy.
- Authors
Jerkins, Terri W.; Jerkins, Randy K.; Franklin, Robbi
- Abstract
Key Clinical Message: Long‐acting pasireotide and bromocriptine provided biochemical control of growth hormone and prolactin in a patient with plurihormonal pituitary macroadenoma, allowing near‐complete tumor excision while restoring pituitary function and avoiding adjunctive radiotherapy. Pasireotide initiation resulted in hyperglycemia, which stabilized after a few months and resolved upon pasireotide discontinuation (ACCESS; NCT01995734). Long‐acting pasireotide and bromocriptine provided biochemical control of growth hormone and prolactin in a patient with plurihormonal pituitary macroadenoma, allowing near‐complete tumor excision while restoring pituitary function and avoiding adjunctive radiotherapy. Pasireotide initiation resulted in hyperglycemia, which stabilized after a few months and resolved upon pasireotide discontinuation (ACCESS; NCT01995734).
- Subjects
DOPAMINE agonists; SOMATOTROPIN; HYPERGLYCEMIA; PROLACTIN
- Publication
Clinical Case Reports, 2019, Vol 7, Issue 3, p445
- ISSN
2050-0904
- Publication type
Article
- DOI
10.1002/ccr3.1961