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- Title
Can Multiparametric Prostate MRI Diagnose Cases with a Gleason Score of 3+3 in Prostate Biopsy Upgrade Patients in Radical Resection Material?
- Authors
VELİOĞLU, Bayram; GÜLTEKİN, Mehmet Ali
- Abstract
Introduction: Prostate cancer is the second most common cancer in men. The pathological grading of prostate cancer was performed using the Gleason scoring (GS) system. In our study, we aimed to identify cases with an elevated stage based on preoperative magnetic resonance (MR) findings in patients with a GS of 6 on transrectal ultrasound (TRUS) biopsy. Method: The data of 22 prostate cancer patients with GS 3+3 were retrospectively examined. Patients were divided into two groups based on the final GS from radical prostatectomy material: GS 3+3 (group 1, n=6) and higher GS (group 2, n=16). Age, lesion size, prostate volume, prostate-specifc antigen (PSA) value, and PSA index were compared between the two groups. apparent diffusion coefficient (ADC) values were measured using a region of interest from diffusion-weighted images obtained with two different techniques (b values of 800 and 1500), and early arterial phase contrast enhancement features were recorded in dynamic contrast-enhanced examinations. Results: At the end of this preliminary study, cancer progression was observed in 72% of patients. Group 1 (mean age 57±3.9) were younger and had smaller lesions compared with group 2, (p=0.009, p=0.045). There was no significant difference in MR-guided biopsy time and biopsy-surgery time between the two groups (p>0.05). No significant differences were found in prostate volume, PSA value, PSA index, and early arterial contrast enhancement pattern between the two groups (p>0.05). ADC values were significantly higher in group 1 (p=0.011, p=0.009). Conclusion: In cases with GS 6 from TRUS biopsy, the detection of younger patients, smaller lesions, and higher ADC values may indicate that the final GS will not increase, suggesting a more conservative approach in these cases.
- Subjects
PROSTATE cancer; PROSTATE biopsy; GLEASON grading system; ENDORECTAL ultrasonography; PROSTATE cancer patients; PROSTATE
- Publication
Bezmialem Science, 2024, Vol 13, pS55
- ISSN
2148-2373
- Publication type
Abstract