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- Title
What is a clinically relevant change on the HIT-6 questionnaire? An estimation in a primary-care population of migraine patients.
- Authors
Smelt, Antonia FH; Assendelft, Willem JJ; Terwee, Caroline B; Ferrari, Michel D; Blom, Jeanet W
- Abstract
Objective: To interpret questionnaire scores, clinicians and researchers need to know what change in score reflects ameaningful change in the condition of an individual patient, and what difference reflects a meaningful difference betweengroups. These values differ between different populations.We determined the within-person minimally important change(MIC) and the between-group minimally important difference (MID) of the Headache Impact Test-6 (HIT-6) questionnairein a primary-care population of migraine patients.Methods: We included 490 patients who participated in a clinical trial on the treatment of migraine in primary care. Wecompared their change scores on the HIT-6 questionnaire between baseline and at three-months follow-up with theanswers to two anchor questions according to the 'mean change approach' and the 'ROC curve approach'.Results: The within-person MIC was estimated to be between -2.5 points (mean change approach) and -6 points (ROCcurve approach). The choice for the within-person MIC value depends on the consequences of false positives and falsenegatives in a particular setting. The between-group MID was estimated at -1.5 points.Conclusions: We determined the within-person MIC and between-group MID for the HIT-6 in a prim
- Subjects
HEADACHE; MIGRAINE; PRIMARY care; MEDICAL care; HEAD diseases; PATIENTS
- Publication
Cephalalgia, 2014, Vol 34, Issue 1, p29
- ISSN
0333-1024
- Publication type
Article
- DOI
10.1177/0333102413497599