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- Title
Association of Vitamin D 25(OH)D Deficiency as a Risk Factor for Pre-Eclampsia.
- Authors
Aziz, Hanifa; Abrar, Faiza; Gul, Seema; Masud, Atikka; Awan, Shabnam Naseer; Qamar, Saima
- Abstract
Background: Pre-eclampsia is the major cause of maternal and fetal morbidity and mortality. Research shows the role of Vitamin deficiency in the pathogenesis of pre-eclampsia. The objective of this study was to determine the association between pre-eclampsia and Vitamin D [25(OH) D] deficiency in our pregnant population. Methods: This was a case-control study, conducted at Outpatient and inpatient Departments of Obstetrics & Gynecology, Combined Military Hospital, Multan from September 2019 to March 2020. A total of 60 patients (30 cases (with pre-eclampsia) and 30 controls (without pre-eclampsia) were included in the study using the convenience (non-probability) sampling technique. After taking informed consent, baseline data including age, gestational age and duration of sun exposure was noted. Blood samples for Vitamin D [25(OH) D] levels were collected aseptically from fresh peripheral venous pricks from cases and controls. Vitamin D [25(OH) D] levels were measured and categorized as adequate and deficient as per operational definitions. All obtained information was recorded in a structured Performa keeping the confidentiality of the patients. Results: Out of 60 patients (n=60) 30 were cases (with pre-eclampsia) and 30 were controls (without pre-eclampsia). The mean age (years) of patients in our study was 23.32+4.34, whereas the frequencies of Vitamin D [25 (OH)] D deficiency among cases and control groups were 18 (60.0%) and 3 (10.0%) respectively. The difference was statistically significant (p-value 0.000). Conclusion: Vitamin D [25 (OH)] D deficiency was found to be more in patients with pre-eclampsia as compared to those without pre-eclampsia.
- Subjects
ECLAMPSIA; VITAMIN D; PREECLAMPSIA; VITAMIN deficiency; MILITARY hospitals; GESTATIONAL age
- Publication
Pakistan Journal of Public Health, 2021, Vol 11, Issue 3, p178
- ISSN
2225-0891
- Publication type
Article
- DOI
10.32413/pjph.v11i3.813