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- Title
Metastatic Grade II simple tubulopapillary mammary carcinoma in a free-living female maned wolf (Chrysocyon brachyurus).
- Authors
de Oliveira Junior, Ivam Moreira; de Oliveira Reis, Matheus; Cata Preta, Carolina de Oliveira; Nunes, Maíra Meira; da Cruz Ferreira, Daiane; Corrêa Abdalla, Daniella; Mesquita Favoretto, Samantha; Suzan Varaschin, Mary
- Abstract
This study described the pathological aspects of a metastatic grade II simple tubulopapillary mammary carcinoma in a freeliving senile female maned wolf (Chrysocyon brachyurus). The diagnosis was based on histopathological findings of malignant epithelial cells arranged in tubular and papillary patterns, with marked anisocytosis and anisokaryosis and metastases to regional lymph nodes, lungs, parietal pleura, and pericardium. Also associated to positive immunolabeling of neoplastic cells for Cytokeratin AE1/AE3 and negative for P63, Calponin and Cox-2, added to the cell proliferation index of 26.8%. The findings demonstrated that free-ranging wild canids develop mammary neoplasms similar to those observed in domestic canids.
- Subjects
METASTASIS; LYMPHATIC metastasis; CARCINOMA; CANCER cells; EPITHELIAL cells; CANIDAE; CELL proliferation; PERICARDIUM
- Publication
Ciência Rural, 2024, Vol 54, Issue 5, p1
- ISSN
0103-8478
- Publication type
Case Study
- DOI
10.1590/0103-8478cr20230063