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- Title
EPIDEMIOLOGY AND CLINICAL EVOLUTION OF CONGENITAL ANOMALIES OF THE KIDNEY AND URINARY TRACT.
- Authors
Isac, Raluca; M., Gafencu; Olariu, Cristina; Cerbu, Simona; A., Ligescu; E. S., Boia
- Abstract
Congenital anomalies of the kidney and urinary tract (CAKUT) are characterized by structural and functional abnormalities of kidney, collecting system, bladder, and urethra. These anomalies are the most commonly diagnosed malformations in the prenatal and postnatal period and constitute the leading cause of Chronic Kidney Disease (CKD) in children, worldwide. CAKUT can be identified as single malformation or it can be part of a complex malformation. Classification of CAKUT on embryological basis consists of: abnormalities in the renal parenchymal development, aberrant embryonic migration and abnormalities of the collecting system. We analyzed 20,326 children admitted in Children Emergency Hospital Timisoara between January 2015 and March 2016 for different pathologies in a cross-sectional study. The prevalence of children with CAKUT was high in our study 5.3‰, with an incidence of 1.5‰ per year. CAKUT is difficult to detect since there is no significant clinical manifestations in early ages. Clinically, CAKUT are silent most of the time, UTI is the most frequent initial distress clue as it was present in 54.12% of cases by the time of diagnosis. Abdominal ultrasound is the preferred method of screening for CAKUT and it should be recommended as a routine of children's physical examination.
- Subjects
KIDNEY abnormalities; URINARY organ abnormalities; EPIDEMIOLOGY
- Publication
Jurnalul Pediatrului, 2017, Vol 20, Issue 77-78, p52
- ISSN
2360-4557
- Publication type
Article