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Periplasmic binding proteins Bug69 and Bug27 from Bordetella pertussis are in vitro high‐affinity quinolinate binders with a potential role in NAD biosynthesis.
Published in:
FEBS Open Bio, 2024, v. 14, n. 10, p. 1718, doi. 10.1002/2211-5463.13876
By:
- Sorci, Leonardo;
- Minazzato, Gabriele;
- Amici, Adolfo;
- Mazzola, Francesca;
- Raffaelli, Nadia
Publication type:
Article
Nicotinate phosphoribosyltransferase: a novel antiinfective target? (585.11).
Published in:
FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.585.11
By:
- Sorci, Leonardo;
- Cheltsov, Anton;
- Massaccesi, Luca;
- Galeazzi, Roberta
Publication type:
Article
A Versatile Continuous Fluorometric Enzymatic Assay for Targeting Nicotinate Phosphoribosyltransferase.
Published in:
Molecules, 2023, v. 28, n. 3, p. 961, doi. 10.3390/molecules28030961
By:
- Minazzato, Gabriele;
- Marangoni, Elisa;
- Fortunato, Carlo;
- Petrelli, Riccardo;
- Cappellacci, Loredana;
- Del Bello, Fabio;
- Sorci, Leonardo;
- Gasparrini, Massimiliano;
- Piacente, Francesco;
- Bruzzone, Santina;
- Raffaelli, Nadia
Publication type:
Article
Biological Activities of the Essential Oil from Erigeron floribundus.
Published in:
Molecules, 2016, v. 21, n. 8, p. 1065, doi. 10.3390/molecules21081065
By:
- Petrelli, Riccardo;
- Orsomando, Giuseppe;
- Sorci, Leonardo;
- Maggi, Filippo;
- Ranjbarian, Farahnaz;
- Biapa Nya, Prosper C.;
- Petrelli, Dezemona;
- Vitali, Luca A.;
- Lupidi, Giulio;
- Quassinti, Luana;
- Bramucci, Massimo;
- Hofer, Anders;
- Cappellacci, Loredana
Publication type:
Article
Small extracellular vesicles deliver miR-21 and miR-217 as pro-senescence effectors to endothelial cells.
Published in:
Journal of Extracellular Vesicles, 2020, v. 9, n. 1, p. 1, doi. 10.1080/20013078.2020.1725285
By:
- Mensà, Emanuela;
- Guescini, Michele;
- Giuliani, Angelica;
- Bacalini, Maria Giulia;
- Ramini, Deborah;
- Corleone, Giacomo;
- Ferracin, Manuela;
- Fulgenzi, Gianluca;
- Graciotti, Laura;
- Prattichizzo, Francesco;
- Sorci, Leonardo;
- Battistelli, Michela;
- Monsurrò, Vladia;
- Bonfigli, Anna Rita;
- Cardelli, Maurizio;
- Recchioni, Rina;
- Marcheselli, Fiorella;
- Latini, Silvia;
- Maggio, Serena;
- Fanelli, Mirco
Publication type:
Article
Small extracellular vesicles deliver miR‐21 and miR‐217 as pro‐senescence effectors to endothelial cells.
Published in:
Journal of Extracellular Vesicles, 2020, v. 9, n. 1, p. 1, doi. 10.1080/20013078.2020.1725285
By:
- Mensà, Emanuela;
- Guescini, Michele;
- Giuliani, Angelica;
- Bacalini, Maria Giulia;
- Ramini, Deborah;
- Corleone, Giacomo;
- Ferracin, Manuela;
- Fulgenzi, Gianluca;
- Graciotti, Laura;
- Prattichizzo, Francesco;
- Sorci, Leonardo;
- Battistelli, Michela;
- Monsurrò, Vladia;
- Bonfigli, Anna Rita;
- Cardelli, Maurizio;
- Recchioni, Rina;
- Marcheselli, Fiorella;
- Latini, Silvia;
- Maggio, Serena;
- Fanelli, Mirco
Publication type:
Article
The Prospective Synergy of Antitubercular Drugs With NAD Biosynthesis Inhibitors.
Published in:
Frontiers in Microbiology, 2021, v. 11, p. N.PAG, doi. 10.3389/fmicb.2020.634640
By:
- Rohde, Kyle H.;
- Sorci, Leonardo
Publication type:
Article
Enzymology of extracellular NAD metabolism.
Published in:
Cellular & Molecular Life Sciences, 2021, v. 78, n. 7, p. 3317, doi. 10.1007/s00018-020-03742-1
By:
- Gasparrini, Massimiliano;
- Sorci, Leonardo;
- Raffaelli, Nadia
Publication type:
Article
Characterization of bacterial NMN deamidase as a Ser/Lys hydrolase expands diversity of serine amidohydrolases.
Published in:
FEBS Letters, 2014, v. 588, n. 6, p. 1016, doi. 10.1016/j.febslet.2014.01.063
By:
- Sorci, Leonardo;
- Brunetti, Lucia;
- Cialabrini, Lucia;
- Mazzola, Francesca;
- Kazanov, Marat D.;
- D’Auria, Sabato;
- Ruggieri, Silverio;
- Raffaelli, Nadia
Publication type:
Article
Genomics-Guided Analysis of NAD Recycling Yields Functional Elucidation of COG1058 as a New Family of Pyrophosphatases.
Published in:
PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0065595
By:
- Cialabrini, Lucia;
- Ruggieri, Silverio;
- Kazanov, Marat D.;
- Sorci, Leonardo;
- Mazzola, Francesca;
- Orsomando, Giuseppe;
- Osterman, Andrei L.;
- Raffaelli, Nadia
Publication type:
Article
Glutamine versus Ammonia Utilization in the NAD Synthetase Family.
Published in:
PLoS ONE, 2012, v. 7, n. 6, p. 1, doi. 10.1371/journal.pone.0039115
By:
- De Ingeniis, Jessica;
- Kazanov, Marat D.;
- Shatalin, Konstantin;
- Gelfand, Mikhail S.;
- Osterman, Andrei L.;
- Sorci, Leonardo
Publication type:
Article
Transcriptional regulation of NAD metabolism in bacteria: genomic reconstruction of NiaR (YrxA) regulon.
Published in:
Nucleic Acids Research, 2008, v. 36, n. 6, p. 2032, doi. 10.1093/nar/gkn046
By:
- Rodionov, Dmitry A.;
- Li, Xiaoqing;
- Rodionova, Irina A.;
- Yang, Chen;
- Sorci, Leonardo;
- Dervyn, Etienne;
- Martynowski, Dariusz;
- Zhang, Hong;
- Gelfand, Mikhail S.;
- Osterman, Andrei L.
Publication type:
Article
NAD-Biosynthetic and Consuming Enzymes as Central Players of Metabolic Regulation of Innate and Adaptive Immune Responses in Cancer.
Published in:
Frontiers in Immunology, 2019, p. 1, doi. 10.3389/fimmu.2019.01720
By:
- Audrito, Valentina;
- Managò, Antonella;
- Gaudino, Federica;
- Sorci, Leonardo;
- Messana, Vincenzo Gianluca;
- Raffaelli, Nadia;
- Deaglio, Silvia
Publication type:
Article
Extracellular nicotinate phosphoribosyltransferase binds Toll like receptor 4 and mediates inflammation.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-12055-2
By:
- Managò, Antonella;
- Audrito, Valentina;
- Mazzola, Francesca;
- Sorci, Leonardo;
- Gaudino, Federica;
- Gizzi, Katiuscia;
- Vitale, Nicoletta;
- Incarnato, Danny;
- Minazzato, Gabriele;
- Ianniello, Alice;
- Varriale, Antonio;
- D'Auria, Sabato;
- Mengozzi, Giulio;
- Politano, Gianfranco;
- Oliviero, Salvatore;
- Raffaelli, Nadia;
- Deaglio, Silvia
Publication type:
Article
Synthesis, Biological, and Computational Evaluations of Conformationally Restricted NAD-Mimics as Discriminant Inhibitors of Human NMN-Adenylyltransferase Isozymes.
Published in:
Pharmaceuticals (14248247), 2024, v. 17, n. 6, p. 739, doi. 10.3390/ph17060739
By:
- Matteucci, Federica;
- Ferrati, Marta;
- Spinozzi, Eleonora;
- Piergentili, Alessia;
- Del Bello, Fabio;
- Giorgioni, Gianfabio;
- Sorci, Leonardo;
- Petrelli, Riccardo;
- Cappellacci, Loredana
Publication type:
Article
Properly Substituted Benzimidazoles as a New Promising Class of Nicotinate Phosphoribosyltransferase (NAPRT) Modulators.
Published in:
Pharmaceuticals (14248247), 2023, v. 16, n. 2, p. 189, doi. 10.3390/ph16020189
By:
- Baldassarri, Cecilia;
- Giorgioni, Gianfabio;
- Piergentili, Alessandro;
- Quaglia, Wilma;
- Fontana, Stefano;
- Mammoli, Valerio;
- Minazzato, Gabriele;
- Marangoni, Elisa;
- Gasparrini, Massimiliano;
- Sorci, Leonardo;
- Raffaelli, Nadia;
- Cappellacci, Loredana;
- Petrelli, Riccardo;
- Del Bello, Fabio
Publication type:
Article
Inhibition of the NAD salvage pathway in schistosomes impairs metabolism, reproduction, and parasite survival.
Published in:
PLoS Pathogens, 2020, v. 16, n. 5, p. 1, doi. 10.1371/journal.ppat.1008539
By:
- Schultz, Michael D.;
- Dadali, Tulin;
- Jacques, Sylvain A.;
- Muller-Steffner, Hélène;
- Foote, Jeremy B.;
- Sorci, Leonardo;
- Kellenberger, Esther;
- Botta, Davide;
- Lund, Frances E.
Publication type:
Article

Found: 17