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- Title
Green-Blue Discolouration of Brain at Autopsy: A Case Report.
- Authors
Saritha S. R.; Greeshma C. K.; Sreedevi C. S.
- Abstract
Methylene blue is a solid; its water solution is deep blue. It has been described as "the first fully synthetic drug used in medicine." Methylene blue was first prepared in 1876 by German chemist Heinrich Caro. It is on the World Health Organization's List of Essential Medicines. It has been increasingly used in the management of refractory distributive shock. A 16 years old boy following liver transplantation developed septicemia. During autopsy when dissecting brain, grey matter showed colour change from grey to green-blue in a few seconds. Green-blue discolouration of brain was an incidental finding in this case and when back referred it was found that young male developed acute liver failure and had undergone liver transplantation. Following transplant rejection he developed refractory hypotension, septic shock and multiple organ dysfunction syndrome. So in that critical condition methylene blue was given which is an effective drug for refractory shock.
- Subjects
BRAIN; GRAFT rejection; AUTOPSY; MULTIPLE organ failure; LIVER transplantation; HYPOTENSION; ACUTE diseases; LIVER failure; METHYLENE blue; SEPTIC shock
- Publication
Medico-Legal Update, 2022, Vol 22, Issue 4, p63
- ISSN
0971-720X
- Publication type
Article
- DOI
10.37506/mlu.v22i4.3335