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- Title
A randomized controlled trial to investigate the impact of a low glycemic Index (GI) diet on body mass index in obese adolescents.
- Authors
Kong, Alice P. S.; Kai Chow Choi; Chan, Ruth S. M.; Lok, Kris; Ozaki, Risa; Li, Albert M.; Chung Shun Ho; Chan, Michael H. M.; Sea, Mandy; Henry, C. Jeyakumar; Chan, Juliana C. N.; Woo, Jean
- Abstract
Background The role of a low glycemic index (GI) diet in the management of adolescent obesity remains controversial. In this study, we aim to evaluate the impact of low GI diet versus a conventional Chinese diet on the body mass index (BMI) and other obesity indices of obese adolescents. Methods Obese adolescents aged 15–18 years were identified from population-recruited, territory-wide surveys. Obesity was defined as BMI ≥95th percentile of Hong Kong local age- and sexspecific references. Eligible subjects were randomized to either an intervention with low GI diet (consisting of 45-50% carbohydrate, 30-35% fat and 15-20% protein) or conventional Chinese diet as control (consisting of 55-60% carbohydrate, 25-30% fat and 10-15% protein). We used random intercept mixed effects model to compare the differential changes across the time points from baseline to month 6 between the 2 groups. Results 104 obese adolescents were recruited (52 in low GI group and 52 in control group; 43.3% boys). Mean age was 16.7 ± 1.0 years and 16.8 ±1.0 years in low GI and control group respectively. 58.7% subjects completed the study at 6 months (65.4% in low GI group and 51.9% in control group). After adjustment for age and sex, subjects in the low GI group had a significantly greater reduction in obesity indices including BMI, body weight and waist circumference (WC) compared to subjects in the control group (all p <0.05). After further adjustment for physical activity levels, WC was found to be significantly lower in the low GI group compared to the conventional group (p = 0.018). Conclusion Low GI diet in the context of a comprehensive lifestyle modification program may be an alternative to conventional diet in the management of obese adolescents. Trial registration number ClinicalTrials.gov Ref. No: NCT 01278563
- Subjects
GLYCEMIC index; DIET research; BODY mass index; OBESITY; TEENAGERS
- Publication
BMC Public Health, 2014, Vol 14, Issue 1, p1
- ISSN
1471-2458
- Publication type
Article
- DOI
10.1186/1471-2458-14-180