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- Title
Use of drug-coated balloon instead of drug-eluting stent for pediatric cardiac allograft vasculopathy.
- Authors
Hirose, Masaki; Narita, Jun; Hashimoto, Kazuhisa; Ishii, Ryo; Ishida, Hidekazu; Ozono, Keiichi
- Abstract
Cardiac allograft vasculopathy (CAV) sometimes leads to restenosis, even after percutaneous transcatheter intervention. Recently, drug-coated balloons (DCBs) have been successfully used to treat coronary artery disease, especially CAVs, in adults. However, no studies have used DCBs in pediatric CAVs. We encountered a patient with CAV who underwent cardiac transplantation for restrictive cardiomyopathy at the age of 2 years. Nine years after the transplantation, severe stenosis of the proximal left anterior descending branch was observed. Considering the patient's young age and the possibility of restenosis, we performed an intervention with DCB. Follow-up conducted 7 months after the intervention showed no restenosis. Cardiac coronary artery lesions following transplantation are more likely to result in restenosis earlier than arteriosclerotic lesions. In pediatric patients, restenosis might require multiple stents and prolonged antiplatelet therapy. Our findings provide evidence supporting the possibility of an effective treatment of CAV in children.
- Subjects
CARDIOVASCULAR surgery; DRUG delivery systems; PATIENT aftercare; HOMOGRAFTS; TRANSLUMINAL angioplasty; DRUG-eluting stents; CARDIOMYOPATHIES; SURGICAL stents; CORONARY restenosis; PEDIATRIC cardiology; TREATMENT effectiveness; EVEROLIMUS; CORONARY artery disease; IMMUNOSUPPRESSIVE agents; VASCULAR diseases; HEART diseases; TACROLIMUS; EQUIPMENT &; supplies
- Publication
Annals of Pediatric Cardiology, 2023, Vol 16, Issue 1, p45
- ISSN
0974-2069
- Publication type
Article
- DOI
10.4103/apc.apc_47_22