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- Title
The Symbiotic Relationship between a Clinical Hematologist and Hematopathologist in the Management of Children with Cancer.
- Authors
Totadri, Sidharth; Geevar, Tulasi; Arunachalam, Arun Kumar
- Abstract
A bone marrow test was performed with aspirate samples sent to the flow cytometry, molecular hematology, and cytogenetics laboratories. At the end of induction chemotherapy, a repeat bone marrow showed no residual leukemic blasts, and a flow cytometry-based minimal residual disease (MRD) was reported by the hematopathologist to be 0.15% (positive MRD taken as >=0.01%). Hematological malignancies, namely, leukemias and lymphomas comprise the major part of clinical practice for most centers that manage children with cancer. A child with severe musculoskeletal pains due to leukemia may be misdiagnosed as juvenile rheumatoid arthritis, and an astute hematopathologist can call the clinician after seeing the blood smear to prompt a bone marrow test before starting steroid therapy.
- Subjects
CHILDHOOD cancer; MEDICAL personnel; BLOOD diseases; HEMATOLOGISTS; HEMATOLOGIC malignancies; TUMOR lysis syndrome
- Publication
Indian Journal of Medical & Paediatric Oncology, 2023, Vol 44, Issue 5, p460
- ISSN
0971-5851
- Publication type
Article
- DOI
10.1055/s-0043-1764367