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- Title
Hypopigmented Cutaneous Langerhans Cell Histiocytosis in a Hispanic Infant.
- Authors
Anny Xiao; Wonwoo Shon
- Abstract
This article discusses a rare case of hypopigmented cutaneous Langerhans Cell Histiocytosis (LCH) in a Hispanic infant. LCH is a rare inflammatory neoplasia that primarily affects children and can involve multiple organs. The hypopigmented variant of cutaneous LCH is exclusively found in patients with skin of color. Diagnosis of LCH can be challenging due to the variability of skin lesions. This case emphasizes the importance of timely diagnosis and monitoring for disease recurrence or progression. Additionally, the article presents a PubMed search that found 17 similar cases of LCH presenting as hypopigmented skin lesions in patients with skin of color. The lesions were commonly found on the trunk and extremities, with onset typically occurring at 1 month of age. While most patients experienced spontaneous regression, some cases involved systemic involvement. The article highlights the need to consider LCH in the differential diagnosis of hypopigmented skin eruptions in infants with darker skin types and emphasizes the importance of prompt diagnosis and ongoing surveillance.
- Subjects
LANGERHANS-cell histiocytosis; BLOOD cell count; INFANTS
- Publication
Cutis, 2024, Vol 113, Issue 5, pE25
- ISSN
0011-4162
- Publication type
Article
- DOI
10.12788/cutis.1021