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- Title
Cytotoxicity of amorphous calcium phosphate multifunctional composite coatings on titanium obtained by in situ anodization/anaphoretic deposition.
- Authors
PANTOVIĆ PAVLOVIĆ, MARIJANA R.; PAVLOVIĆ, MIROSLAV M.; KOVAČINA, JOVANKA N.; STANOJEVIĆ, BORIS P.; STEVANOVIĆ, JASMINA S.; PANIĆ, VLADIMIR V.; IGNJATOVIĆ, NENAD L.
- Abstract
The cytotoxicity of amorphous calcium phosphate (ACP) and chitosan lactate (ChOL) multifunctional and hybrid composite coatings on MRC-5 human lung fibroblast cell line was elucidated. ACP/TiO2 and ACP/TiO2//ChOL were deposited onto Ti by a novel in situ anodization/anaphoretic process at constant voltage. Cytotoxicity tests showed that there was no significant decrease in the survival of healthy MRC-5 cells exposed to composite samples without chitosan lactate, while there was an increase in the number of viable cells in the sample containing ChOL. These findings show that there was improved cell proliferation, differentiation and cell viability in the ChOL-containing sample, which makes ACP/TiO2/ChOL coating a good candidate for applications in medicine and stomatology.
- Subjects
CALCIUM phosphate; TITANIUM composites; PHOSPHATE coating; COMPOSITE coating; CELL differentiation; CHITOSAN; CELL proliferation
- Publication
Journal of the Serbian Chemical Society, 2021, Vol 86, Issue 6, p555
- ISSN
0352-5139
- Publication type
Article
- DOI
10.2298/JSC210211024P