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- Title
Outpatient opioid prescribing by Alzheimer's diagnosis among older adults with pain in United States.
- Authors
Huang, Yinan; Aparasu, Rajender R; Varisco, Tyler J
- Abstract
Objective: To examine opioid prescribing practices for pain in older adults with and without Alzheimer's Disease and Related Dementias (ADRD). Methods: This cross-sectional study used National Ambulatory Medical Care Survey data (2014–2016, and 2018). Adults aged ≥ 50 years with pain were analyzed. Prescribing of opioid and concomitant sedative prescriptions (including benzodiazepines, Z-drugs, and barbiturates) were identified by the Multum lexicon code. Multivariable logistic regression evaluated the risk of opioid prescribing or co-prescribing of opioid and sedative associated with ADRD in older adults with pain. Results: There were 13,299 office visits in older adults with pain, representing 451.75 million visits. Opioid prescribing occurred in 27.19%; 30% involved co-prescribing of opioids and sedatives. ADRD was not associated with opioid prescribing or co-prescribing of opioid and sedative therapy. Conclusions: Opioid and sedatives are commonly prescribed in older adults with pain. Longitudinal studies need to understand the etiology and chronicity of opioid use in older patients, specifically with ADRD. Highlights: This national study examined the opioid prescribing practices for pain in older adults with and without Alzheimer's Disease and Related Dementias (ADRD). The study found about 30% of visits for older adults with pain resulted in opioid prescriptions, and the co-prescribing of sedatives were noted in 30% of these visits made by older adults with pain where an opioid were prescribed. No significant difference exists between ADRD vs. non-ADRD groups in receiving opioid prescriptions or co-prescription of opioids and sedatives among the visits with pain. Future research should aim to understand the health outcomes associated with opioid prescribing and concomitant receipt of sedatives in ADRD.
- Subjects
UNITED States; ALZHEIMER'S disease; OLDER people; DRUG prescribing; OPIOIDS; MEDICAL care surveys
- Publication
BMC Geriatrics, 2023, Vol 23, Issue 1, p1
- ISSN
1471-2318
- Publication type
Article
- DOI
10.1186/s12877-023-04115-6