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- Title
The complex interplay among hepatocytes and immune cells at the crossroad between inflammation and cholesterol metabolism in hyperglycemia.
- Authors
Bifulco, Maurizio; Pisanti, Simona; Ciaglia, Elena
- Abstract
An intriguing piece of evidence for the inflammatory story of type 2 diabetes has come to the light. A recent study by Okin and colleagues adds new clues to the interplay between cholesterol metabolism and immunity and how it impacts glucose homeostasis in inflammatory conditions. But some questions are a still unsolved conundrum. Here we suggest to better dissect the regulatory mechanism of Mevalonate pathway and to underpin a new causative link between immunometabolic dysregulation and diabetes.
- Publication
Endocrine (1355008X), 2017, Vol 58, Issue 1, p21
- ISSN
1355-008X
- Publication type
Article
- DOI
10.1007/s12020-017-1254-0