The article discusses the research about the role of Caulobacter crescentus as proteotoxic stress. It references the study "Proteotoxic stress induces a cell-cyle arrest by stimulating Lon to degrade the replication initiator DnaA," by K. Jonas and colleagues . It states that C. crescentus stimulates cell cycle arrest and DNA replication pausing by degradation of the replication initiator DnaA by the protease Lon.