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- Title
Viral evolution: Fooling the coronavirus proofreading machinery.
- Authors
Hofer, Ursula
- Abstract
The article reports on a study presented by Smith and colleagues regarding the proofreading activity of polymerase of RNA viruses. It states that in the case of severe acute respiratory syndrome coronavirus (SARS-CoV), the exoribonuclease domain (ExoN) provides proofreading activity that prevents virus from mutagenesis. It notes that the research study aims to describe the hypotheses that ExoN is a proofreading enzyme.
- Subjects
PROOFREADING; RNA polymerases; SARS disease; CORONAVIRUSES; EXORIBONUCLEASES; MUTAGENESIS; ENZYMES
- Publication
Nature Reviews Microbiology, 2013, Vol 11, Issue 10, p662
- ISSN
1740-1526
- Publication type
Article
- DOI
10.1038/nrmicro3125