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- Title
Lithiation of deoxypeganine and chiral synthesis of deoxypeganine derivatives.
- Authors
Shakhidoyatov, Kh. M.; Coldham, I.; Ibragimov, T. F.
- Abstract
method was developed for lithiation of deoxypeganine. The reaction of organolithium deoxypeganine derivatives with isobutyraldehyde and benzaldehyde to produce its derivatives was studied. A chiral synthesis of substituted deoxypeganines was performed. The synthesized diastereomers and enantiomers were separated successfully using HPLC and a chiral column.
- Subjects
CHIRAL drugs; DIASTEREOISOMERS; ORGANOLITHIUM compounds; BENZALDEHYDE; HIGH performance liquid chromatography
- Publication
Chemistry of Natural Compounds, 2011, Vol 46, Issue 6, p929
- ISSN
0009-3130
- Publication type
Article
- DOI
10.1007/s10600-011-9785-8