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- Title
A Quasi-experimental Study Evaluating the Effectiveness of Cryotherapy on Chemotherapy-induced Oral Mucositis Prevention at the Uganda Cancer Institute.
- Authors
Kamulegeya, Adriane; Rwenyonyi, Charles Mugisha; Orem, Jackson; Nakanjako, Damalie
- Abstract
Introduction. Low-cost interventions such as cryotherapy are not routinely practiced in sub-Saharan Africa to prevent chemotherapeutic-induced oral mucositis. We investigated the feasibility and effect of cryotherapy on oral mucositis at the Uganda Cancer Institute. Methods. This was a quasi-experimental nonequivalent research study design. We had two groups with each group meant to have 100 participants. We analyzed based on participants who underwent the protocol procedures. Results. Only cancer types were significantly different between the control and intervention groups (χ2=31.09, df =18, p=.030). Twenty percent (n=19) out of the 95, while 8.2% (n=7) out of the 85 in the control and intervention groups respectively developed moderate to severe mucositis (Mantel-Cox and Generalized Wilcoxon p=.026 and p=.031, respectively). Conclusion. The use of cryotherapy in our local setting and many sub-Saharan African countries is feasible and affordable to prevent and control chemotherapy-induced oral mucositis.
- Subjects
UGANDA; STOMATITIS; SPECIALTY hospitals; CLINICAL trials; CANCER chemotherapy; COLD therapy; RESEARCH methodology; SELF-evaluation; MANN Whitney U Test; CANCER treatment; TREATMENT effectiveness; CANCER patients; COMPARATIVE studies; DESCRIPTIVE statistics; QUESTIONNAIRES; RESEARCH funding; DATA analysis; JUDGMENT sampling; DATA analysis software
- Publication
Journal of Health Care for the Poor & Underserved, 2023, Vol 34, Issue 4, p1386
- ISSN
1049-2089
- Publication type
Article
- DOI
10.1353/hpu.2023.a912724