We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
USAGE OF 4-D RADIOTHERAPY IN CONTEMPORARY CANCER MANAGEMENT.
- Authors
BEYZADEOGLU, Murat; SAGER, Omer; DINCOGLAN, Ferrat; UYSAL, Bora; GAMSIZ, Hakan; DEMIRAL, Selcuk
- Abstract
OBJECTIVE: Reducing the treatment-related toxicity of radiation therapy has gained utmost priority in cancer management recently thanks to increased public awareness, improved screening programs, high-tech imaging capabilities and state-of-art therapies leading to earlier detection and long overall survival. In this aspect, management of respiratory motion is currently the key factor of contemporary radiotherapeutic approaches. The use of 4-Dimensional (4-D) radiotherapy is the primary method of respiratory motion management in radiation oncology practice. Herein, the increasing scope of 4-D radiotherapy in cancer management is discussed thoroughly in light of our practical institutional experience and comprehensive literature review. MATERIAL AND METHOD: 4-D radiotherapy is commonly used in the treatment of thoracoabdominal tumors and thoracoabdominal image-guided Stereotactic Body Radiation Therapy (SBRT) for pulmonary metastases, early stage Non-Small Cell Lung Cancer (NSCLC), liver metastases, recurrent pancreatic cancer, and adrenal metastases. During the 2010-2014 years, 44 SBRT applications have been done for 23 patients with pulmonary oligometastasis, 2 patients with early-stage NSCLC, and 19 patients with surrenal-gland metastasis at Gulhane Military Medical Academy Radiation Oncology Department. RESULTS: The incorporation of respiratory motion management strategies into daily radiotherapy practice for mobile tumor targets has allowed highly successful respiratory motion management to spare normal tissues of heart, lungs, and spinal cord. CONCLUSION: The introduction of 4-D radiotherapy in contemporary cancer therapy practice has great potential to improve therapeutic outcomes by providing enhanced normal tissue sparing with excellent respiratory motion management.
- Publication
Balkan Military Medical Review, 2014, Vol 17, p41
- ISSN
1107-6275
- Publication type
Article