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- Title
Avocado-Soybean Unsaponifiables: A Panoply of Potentialities to Be Exploited.
- Authors
Salehi, Bahare; Rescigno, Antonio; Dettori, Tinuccia; Calina, Daniela; Docea, Anca Oana; Singh, Laxman; Cebeci, Fatma; Özçelik, Beraat; Bhia, Mohammed; Beirami, Amirreza Dowlati; Sharifi-Rad, Javad; Sharopov, Farukh; Cho, William C.; Martins, Natália
- Abstract
Avocado and soybean unsaponifiables (ASU) constitute vegetable extracts made from fruits and seeds of avocado and soybean oil. Characterized by its potent anti-inflammatory effects, this ASU mixture is recommended to act as an adjuvant treatment for osteoarthritic pain and slow-acting symptomatic treatment of hip and knee osteoarthritis; autoimmune diseases; diffuse scleroderma and scleroderma-like states (e.g., morphea, sclerodactyly, scleroderma in bands). Besides, it was reported that it can improve the mood and quality of life of postmenopausal women in reducing menopause-related symptoms. This article aims to summarize the studies on biological effects of the avocado-soybean unsaponifiable, its chemical composition, pharmacotherapy as well as applications in autoimmune, osteoarticular and menopausal disorders. Finally, we will also discuss on its safety, toxicological and regulatory practices.
- Subjects
AVOCADO; POSTMENOPAUSE; SOY oil; SCLERODERMA (Disease); SOYBEAN; FRUIT seeds; AUTOIMMUNE diseases
- Publication
Biomolecules (2218-273X), 2020, Vol 10, Issue 1, p1
- ISSN
2218-273X
- Publication type
Article
- DOI
10.3390/biom10010130