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Genomic evolution in Barrett's adenocarcinoma cells: critical roles of elevated hsRAD51, homologous recombination and Alu sequences in the genome.
Published in:
Oncogene, 2011, v. 30, n. 33, p. 3585, doi. 10.1038/onc.2011.83
By:
- Pal, J;
- Bertheau, R;
- Buon, L;
- Qazi, A;
- Batchu, R B;
- Bandyopadhyay, S;
- Ali-Fehmi, R;
- Beer, D G;
- Weaver, D W;
- Shmookler Reis, R J;
- Goyal, R K;
- Huang, Q;
- Munshi, N C;
- Shammas, M A
Publication type:
Article
AT7519, A novel small molecule multi-cyclin-dependent kinase inhibitor, induces apoptosis in multiple myeloma via GSK-3β activation and RNA polymerase II inhibition.
Published in:
Oncogene, 2010, v. 29, n. 16, p. 2325, doi. 10.1038/onc.2009.510
By:
- Santo, L.;
- Vallet, S.;
- Hideshima, T.;
- Cirstea, D.;
- Ikeda, H.;
- Pozzi, S.;
- Patel, K.;
- Okawa, Y.;
- Gorgun, G.;
- Perrone, G.;
- Calabrese, E.;
- Yule, M.;
- Squires, M.;
- Ladetto, M.;
- Boccadoro, M.;
- Richardson, P. G.;
- Munshi, N. C.;
- Anderson, K. C.;
- Raje, N.
Publication type:
Article
Expression of a free gamma heavy chain in serum following autologous stem cell transplantation for IgG kappa multiple myeloma.
Published in:
Bone Marrow Transplantation, 2001, v. 27, n. 6, p. 663, doi. 10.1038/sj.bmt.1702850
By:
- Butch, A W;
- Badros, A;
- Desikan, K R;
- Munshi, N C
Publication type:
Article
Patients with multiple myeloma may safely undergo autologous transplantation despite ongoing RSV infection and no ribavirin therapy.
Published in:
Bone Marrow Transplantation, 1999, v. 24, n. 5, p. 505, doi. 10.1038/sj.bmt.1701946
By:
- Aslan, T;
- Fassas, A B-T;
- Desikan, R;
- Siegel, D;
- Munshi, N C;
- Mehta, J;
- Singhal, S;
- Barlogie, B;
- Anaissie, E
Publication type:
Article
Lymphomatoid granulomatosis following autologous stem cell transplantation.
Published in:
Bone Marrow Transplantation, 1999, v. 23, n. 1, p. 79, doi. 10.1038/sj.bmt.1701513
By:
- Fassas, A;
- Jagannath, S;
- Desikan, K R;
- Shah, H R;
- Shaver, R;
- Waldron, J;
- Munshi, N C;
- Barlogie, B;
- Tricot, G
Publication type:
Article
Bone marrow stromal cells as a vehicle for gene transfer.
Published in:
Gene Therapy, 1999, v. 6, n. 9, p. 1611, doi. 10.1038/sj.gt.3300973
By:
- Ding, L;
- Lu, S;
- Batchu, R B;
- Saylors III, R L;
- Munshi, N C
Publication type:
Article
In vitro packaging of an infectious recombinant adeno-associated virus 2.
Published in:
Gene Therapy, 1997, v. 4, n. 11, p. 1167, doi. 10.1038/sj.gt.3300514
By:
- Ding, L;
- Lu, S;
- Munshi, N C
Publication type:
Article
Selective targeting of IRF4 by synthetic microRNA-125b-5p mimics induces anti-multiple myeloma activity in vitro and in vivo.
Published in:
2015
By:
- Morelli, E;
- Leone, E;
- Cantafio, M E Gallo;
- Di Martino, M T;
- Amodio, N;
- Biamonte, L;
- Gullà, A;
- Foresta, U;
- Pitari, M R;
- Botta, C;
- Rossi, M;
- Neri, A;
- Munshi, N C;
- Anderson, K C;
- Tagliaferri, P;
- Tassone, P
Publication type:
journal article
Targeting PD1-PDL1 immune checkpoint in plasmacytoid dendritic cell interactions with T cells, natural killer cells and multiple myeloma cells.
Published in:
Leukemia (08876924), 2015, v. 29, n. 6, p. 1441, doi. 10.1038/leu.2015.11
By:
- Ray, A;
- Das, D S;
- Song, Y;
- Richardson, P;
- Munshi, N C;
- Chauhan, D;
- Anderson, K C
Publication type:
Article
Anti-tumor activities of selective HSP90α/β inhibitor, TAS-116, in combination with bortezomib in multiple myeloma.
Published in:
2015
By:
- Suzuki, R;
- Hideshima, T;
- Mimura, N;
- Minami, J;
- Ohguchi, H;
- Kikuchi, S;
- Yoshida, Y;
- Gorgun, G;
- Cirstea, D;
- Cottini, F;
- Jakubikova, J;
- Tai, Y-T;
- Chauhan, D;
- Richardson, P G;
- Munshi, N C;
- Utsugi, T;
- Anderson, K C
Publication type:
letter
CSNK1α1 mediates malignant plasma cell survival.
Published in:
2015
By:
- Hu, Y;
- Song, W;
- Cirstea, D;
- Lu, D;
- Munshi, N C;
- Anderson, K C
Publication type:
journal article
Anti-tumor activities of selective HSP90α/β inhibitor, TAS-116, in combination with bortezomib in multiple myeloma.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 510, doi. 10.1038/leu.2014.300
By:
- Suzuki, R;
- Hideshima, T;
- Mimura, N;
- Minami, J;
- Ohguchi, H;
- Kikuchi, S;
- Yoshida, Y;
- Gorgun, G;
- Cirstea, D;
- Cottini, F;
- Jakubikova, J;
- Tai, Y-T;
- Chauhan, D;
- Richardson, P G;
- Munshi, N C;
- Utsugi, T;
- Anderson, K C
Publication type:
Article
CSNK1α1 mediates malignant plasma cell survival.
Published in:
Leukemia (08876924), 2015, v. 29, n. 2, p. 474, doi. 10.1038/leu.2014.202
By:
- Hu, Y;
- Song, W;
- Cirstea, D;
- Lu, D;
- Munshi, N C;
- Anderson, K C
Publication type:
Article
A multiepitope of XBP1, CD138 and CS1 peptides induces myeloma-specific cytotoxic T lymphocytes in T cells of smoldering myeloma patients.
Published in:
Leukemia (08876924), 2015, v. 29, n. 1, p. 218, doi. 10.1038/leu.2014.159
By:
- Bae, J;
- Prabhala, R;
- Voskertchian, A;
- Brown, A;
- Maguire, C;
- Richardson, P;
- Dranoff, G;
- Anderson, K C;
- Munshi, N C
Publication type:
Article
Gene expression profile alone is inadequate in predicting complete response in multiple myeloma.
Published in:
Leukemia (08876924), 2014, v. 28, n. 11, p. 2229, doi. 10.1038/leu.2014.140
By:
- Amin, S B;
- Yip, W-K;
- Minvielle, S;
- Broyl, A;
- Li, Y;
- Hanlon, B;
- Swanson, D;
- Shah, P K;
- Moreau, P;
- van der Holt, B;
- van Duin, M;
- Magrangeas, F;
- Pieter Sonneveld, P;
- Anderson, K C;
- Li, C;
- Avet-Loiseau, H;
- Munshi, N C
Publication type:
Article
Transcription factor-pathway coexpression analysis reveals cooperation between SP1 and ESR1 on dysregulating cell cycle arrest in non-hyperdiploid multiple myeloma.
Published in:
Leukemia (08876924), 2014, v. 28, n. 4, p. 894, doi. 10.1038/leu.2013.233
By:
- Wang, X;
- Yan, Z;
- Fulciniti, M;
- Li, Y;
- Gkotzamanidou, M;
- Amin, S B;
- Shah, P K;
- Zhang, Y;
- Munshi, N C;
- Li, C
Publication type:
Article
Histone deacetylase 3 as a novel therapeutic target in multiple myeloma.
Published in:
Leukemia (08876924), 2014, v. 28, n. 3, p. 680, doi. 10.1038/leu.2013.231
By:
- Minami, J;
- Suzuki, R;
- Mazitschek, R;
- Gorgun, G;
- Ghosh, B;
- Cirstea, D;
- Hu, Y;
- Mimura, N;
- Ohguchi, H;
- Cottini, F;
- Jakubikova, J;
- Munshi, N C;
- Haggarty, S J;
- Richardson, P G;
- Hideshima, T;
- Anderson, K C
Publication type:
Article
Small-molecule multi-targeted kinase inhibitor RGB-286638 triggers P53-dependent and -independent anti-multiple myeloma activity through inhibition of transcriptional CDKs.
Published in:
Leukemia (08876924), 2013, v. 27, n. 12, p. 2366, doi. 10.1038/leu.2013.194
By:
- Cirstea, D;
- Hideshima, T;
- Santo, L;
- Eda, H;
- Mishima, Y;
- Nemani, N;
- Hu, Y;
- Mimura, N;
- Cottini, F;
- Gorgun, G;
- Ohguchi, H;
- Suzuki, R;
- Loferer, H;
- Munshi, N C;
- Anderson, K C;
- Raje, N
Publication type:
Article
Minor clone provides a reservoir for relapse in multiple myeloma.
Published in:
Leukemia (08876924), 2013, v. 27, n. 2, p. 473, doi. 10.1038/leu.2012.226
By:
- Magrangeas, F;
- Avet-Loiseau, H;
- Gouraud, W;
- Lodé, L;
- Decaux, O;
- Godmer, P;
- Garderet, L;
- Voillat, L;
- Facon, T;
- Stoppa, A M;
- Marit, G;
- Hulin, C;
- Casassus, P;
- Tiab, M;
- Voog, E;
- Randriamalala, E;
- Anderson, K C;
- Moreau, P;
- Munshi, N C;
- Minvielle, S
Publication type:
Article
Identification of novel myeloma-specific XBP1 peptides able to generate cytotoxic T lymphocytes: a potential therapeutic application in multiple myeloma.
Published in:
2011
By:
- Bae, J;
- Carrasco, R;
- Lee, A-H;
- Prabhala, R;
- Tai, Y-T;
- Anderson, K C;
- Munshi, N C
Publication type:
journal article
HDAC inhibition by LBH589 affects the phenotype and function of human myeloid dendritic cells.
Published in:
2011
By:
- Song, W.;
- Tai, Y.-T;
- Tian, Z.;
- Hideshima, T.;
- Chauhan, D.;
- Nanjappa, P.;
- Exley, M. A.;
- Anderson, K. C.;
- Munshi, N. C.
Publication type:
journal article
The use of novel agents in the treatment of relapsed and refractory multiple myeloma.
Published in:
2009
By:
- Laubach, J. P.;
- Mahindra, A.;
- Mitsiades, C. S.;
- Schlossman, R. L.;
- Munshi, N. C.;
- Ghobrial, I. M.;
- Carreau, N.;
- Hideshima, T.;
- Anderson, K. C.;
- Richardson, P. G.
Publication type:
journal article
International myeloma working group (IMWG) consensus statement and guidelines regarding the current status of stem cell collection and high-dose therapy for multiple myeloma and the role of plerixafor (AMD 3100).
Published in:
2009
By:
- Giralt, S.;
- Stadtmauer, E. A.;
- Harousseau, J. L.;
- Palumbo, A.;
- Bensinger, W.;
- Comenzo, R. L.;
- Kumar, S.;
- Munshi, N. C.;
- Dispenzieri, A.;
- Kyle, R.;
- Merlini, G.;
- Miguel, J. San;
- Ludwig, H.;
- Hajek, R.;
- Jagannath, S.;
- Blade, J.;
- Lonial, S.;
- Dimopoulos, M. A.;
- Einsele, H.;
- Barlogie, B.
Publication type:
journal article
Preclinical activity of P276-00, a novel small-molecule cyclin-dependent kinase inhibitor in the therapy of multiple myeloma.
Published in:
Leukemia (08876924), 2009, v. 23, n. 5, p. 961, doi. 10.1038/leu.2008.378
By:
- Raje, N.;
- Hideshima, T.;
- Mukherjee, S.;
- Raab, M.;
- Vallet, S.;
- Chhetri, S.;
- Cirstea, D.;
- Pozzi, S.;
- Mitsiades, C.;
- Rooney, M.;
- Kiziltepe, T.;
- Podar, K.;
- Okawa, Y.;
- Ikeda, H.;
- Carrasco, R.;
- Richardson, P. G.;
- Chauhan, D.;
- Munshi, N. C.;
- Sharma, S.;
- Parikh, H.
Publication type:
Article
Lenalidomide inhibits osteoclastogenesis, survival factors and bone-remodeling markers in multiple myeloma.
Published in:
Leukemia (08876924), 2008, v. 22, n. 10, p. 1925, doi. 10.1038/leu.2008.174
By:
- Breitkreutz, I.;
- Raab, M. S.;
- Vallet, S.;
- Hideshima, T.;
- Raje, N.;
- Mitsiades, C.;
- Chauhan, D.;
- Okawa, Y.;
- Munshi, N. C.;
- Richardson, P. G.;
- Anderson, K. C.
Publication type:
Article
Lenalidomide inhibits osteoclastogenesis, survival factors and bone-remodeling markers in multiple myeloma.
Published in:
2008
By:
- Breitkreutz, I;
- Raab, M S;
- Vallet, S;
- Hideshima, T;
- Raje, N;
- Mitsiades, C;
- Chauhan, D;
- Okawa, Y;
- Munshi, N C;
- Richardson, P G;
- Anderson, K C
Publication type:
Correction notice
Telomerase inhibitor GRN163L inhibits myeloma cell growth in vitro and in vivo.
Published in:
2008
By:
- Shammas, M A;
- Koley, H;
- Bertheau, R C;
- Neri, P;
- Fulciniti, M;
- Tassone, P;
- Blotta, S;
- Protopopov, A;
- Mitsiades, C;
- Batchu, R B;
- Anderson, K C;
- Chin, A;
- Gryaznov, S;
- Munshi, N C
Publication type:
journal article
Biological pathways and in vivo antitumor activity induced by Atiprimod in myeloma.
Published in:
Leukemia (08876924), 2007, v. 21, n. 12, p. 2519, doi. 10.1038/sj.leu.2404912
By:
- Neri, P.;
- Tassone, P.;
- Shammas, M.;
- Yasui, H.;
- Schipani, E.;
- Batchu, R. B.;
- Blotta, S.;
- Prabhala, R.;
- Catley, L.;
- Hamasaki, M.;
- Hideshima, T.;
- Chauhan, D.;
- Jacob, G. S.;
- Picker, D.;
- Venuta, S.;
- Anderson, K. C.;
- Munshi, N. C.
Publication type:
Article
Tumor antigen immunization of sibling stem cell transplant donors in multiple myeloma.
Published in:
Bone Marrow Transplantation, 2005, v. 36, n. 4, p. 315, doi. 10.1038/sj.bmt.1705057
By:
- Neelapu, S. S.;
- Munshi, N. C.;
- Jagannath, S.;
- Watson, T. M.;
- Pennington, R.;
- Reynolds, C.;
- Barlogie, B.;
- Kwak, L. W.
Publication type:
Article
Targeting homologous recombination and telomerase in Barrett's adenocarcinoma: impact on telomere maintenance, genomic instability and tumor growth.
Published in:
Oncogene, 2014, v. 33, n. 12, p. 1495, doi. 10.1038/onc.2013.103
By:
- Lu, R;
- Pal, J;
- Buon, L;
- Nanjappa, P;
- Shi, J;
- Fulciniti, M;
- Tai, Y-T;
- Guo, L;
- Yu, M;
- Gryaznov, S;
- Munshi, N C;
- Shammas, M A
Publication type:
Article
Antimyeloma activity of two novel N-substituted and tetraflourinated thalidomide analogs.
Published in:
Leukemia (08876924), 2005, v. 19, n. 7, p. 1253, doi. 10.1038/sj.leu.2403776
By:
- Kumar, S.;
- Raje, N.;
- Hideshima, T.;
- Ishitsuka, K.;
- Roccaro, A.;
- Shiraishi, N.;
- Hamasaki, M.;
- Yasui, H.;
- Munshi, N. C.;
- Richardson, P.;
- Figg, W. D.;
- Anderson, K. C.
Publication type:
Article
Preceding chemotherapy, tumour load and age influence engraftment in multiple myeloma patients mobilized with granulocyte colony-stimulating factor alone.
Published in:
British Journal of Haematology, 2001, v. 112, n. 1, p. 242, doi. 10.1046/j.1365-2141.2001.02498.x
By:
- Desikan, K. R.;
- Tricot, G.;
- Munshi, N. C.;
- Anaissie, E.;
- Spoon, D.;
- Fassas, A.;
- Toor, A.;
- Zangari, M.;
- Badros, A.;
- Morris, C.;
- Vesole, D. H.;
- Siegel, D.;
- Jagannath, S.;
- Barlogie, B.
Publication type:
Article
High-dose therapy with autologous haemopoietic stem cell support for Waldenström's macroglobulinaemia.
Published in:
British Journal of Haematology, 1999, v. 105, n. 4, p. 993, doi. 10.1046/j.1365-2141.1999.01461.x
By:
- Desikan, R.;
- Dhodapkar, M.;
- Siegel, D.;
- Fassas, A.;
- Singh, J.;
- Singhal, S.;
- Mehta, J.;
- Vesole, D.;
- Tricot, G.;
- Jagannath, S.;
- Anaissie, E.;
- Barlogie, B.;
- Munshi, N. C.
Publication type:
Article

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