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- Title
FORMULATION AND CHARACTERIZATION OF POLYMERIC NANOPARTICLES FOR EFFECTIVE TUMOR TARGETING STRATEGIES.
- Authors
Jain, Ritu; Tiwari, Ritesh; Agrawal, O. P.; Shukla, Ajay Kumar
- Abstract
Most popular cancer targeted drug delivery system is polymeric nanoparticles, and it is used as a drug carrier which represents a marvellous path for cancer therapy. Polymeric nanoparticles have following important characteristics that are biodegradability, biocompatibility, nontoxicity, prolonged circulation and a wide payload spectrum of a therapeutic agent. Other outstanding characteristics is unique size and their shape properties for tissue penetration via an active and passive targeting, specific cellular/subcellular trafficking pathways and facile control of cargo release by sophisticated material engineering. The present review covered the preparation method, physico-chemical properties of polymeric nanoparticles, characterization, routes of administration and potential therapeutic applications.
- Subjects
POLYMERIC nanocomposites; DRUG delivery systems; CANCER treatment
- Publication
Journal of Advanced Scientific Research, 2020, Vol 11, p69
- ISSN
0976-9595
- Publication type
Article