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- Title
Nitric Oxide Therapeutics in Pulmonary Vascular Disease.
- Authors
Simon, Marc A.
- Abstract
Clinical trials of inhaled nitrite to treat pulmonary arterial hypertension (PAH) are ongoing. The pathogenesis of PAH involves smooth muscle hypertrophy as a result of endothelial dysfunction and/or chronic vasoconstriction. Nitric oxide (NO) is a potent vasodilator and a primary therapeutic pathway for PAH. This review will address some of the emerging PAH treatment strategies utilizing the NO pathway.
- Subjects
NITRIC oxide; PULMONARY circulation disorders; PULMONARY hypertension; VASODILATORS; BIOMEDICAL engineering
- Publication
Advances in Pulmonary Hypertension, 2014, Vol 13, Issue 3, p134
- ISSN
1933-088X
- Publication type
Article
- DOI
10.21693/1933-088x-13.3.134