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- Title
Fetal gender ratio in recurrent miscarriages.
- Authors
Del Fabro, Anna; Driul, Lorenza; Anis, Omar; Londero, Ambrogio P.; Bertozzi, Serena; Bortotto, Livio; Marchesoni, Diego
- Abstract
Background: The purpose of this study was to evaluate the gender ratio and incidence of chromosomal anomalies in the products of conception (POC) from recurrent miscarriages. Methods: We determined the karyotypes of POC from patients with recurrent spontaneous miscarriages between 1999 and 2009. Results: In total, 313 specimens were successfully karyotyped, with a median gestational age of 10 weeks at miscarriage (interquartile range 8-13); 199 (64%) were females and 114 (36%) were males. In total, 121 (39%) had abnormal karyotypes, the most prevalent of which were chromosome 21 and 16 trisomies, triploidy, and monosomy X. Conclusion: Our findings suggest that female POC might be more susceptible to recurrent miscarriages than male ones during embryogenesis, implantation, and initial fetal development.
- Publication
International Journal of Women's Health, 2011, Vol 3, p213
- ISSN
1179-1411
- Publication type
Article
- DOI
10.2147/IJWH.S20557