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- Title
Estimation of salivary superoxide dismutase levels in chronic periodontitis patients with or without coronary heart disease.
- Authors
Ram, Arunn Jaikumarr; Vishnupriya, V.; Ponnulakshmi, R.; Gayathri, R.; Madhan, K.; Shyamaladevi, B.; Selvaraj, J.
- Abstract
Background: Chronic periodontitis (CP) is an infectious disease which is caused by Gram-negative bacteria, which settles in the subgingival biofilm and leads to the destruction of the soft and hard tissues around the teeth. Aim: The aim of the study was to determine the levels of salivary superoxide dismutase (SOD) levels in CP level. Materials and Methods: The present study was conducted on subjects reporting to the Department of Periodontology at a Saveetha Dental College and Hospitals, SIMATS, Chennai, India. A sample of 15 was determined as the minimum in each group to estimate and to calculate for the statistical analysis. Results: Lower levels of antioxidants in diseased states of CP and coronary heart disease (CHD) point toward the conclusion that the disease process is a result of a balance tipped in favor of the oxidants, with failure of antioxidants to balance the oxidant levels. Conclusion: It is concluded that SOD levels in the saliva are proportionately decreased in CP with CHD and hence salivary SOD levels can be a biomarker for the CP+CHD as a non-invasive method.
- Subjects
INDIA; CHENNAI (India); SUPEROXIDE dismutase; CORONARY disease; HEART diseases; GRAM-negative bacteria; DENTAL schools; SUPEROXIDES
- Publication
Drug Invention Today, 2019, Vol 12, Issue 5, p914
- ISSN
0975-7619
- Publication type
Article