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- Title
A study on antioxidant activity, phenol, and flavonoid content of seedpod of Nelumbo nucifera Gaertn.
- Authors
Ruvanthika, P. N.; Manikandan, S.
- Abstract
Objective: The objective of the present study was to evaluate the presence of phenol, flavonoid, tannin, antioxidant activity, and high-performance liquid chromatography (HPLC) analysis of quercetin (active component of Nelumbo nucifera [NN]) in ethanolic extract of the seedpod of Nelumbo nucifera (NNE). Materials and Methods: Preliminary screening of NNE was done for the presence of phenol, flavonoid, tannin, qualitatively, and quantitatively. Antioxidant activities of the NNE were estimated using extracts of aqueous, acetone, ethanol, and chloroform by in vitro antioxidant assays such as 1,1-diphenyl-2- picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP) assays. Results: Total phenolic content in NNE was 93.45 mg gallic acid equivalents, the total flavonoid content was 295.312 mg/g quercetin equivalents in NNE, and tannin content is 508.7 mg/g tannin equivalents in NNE. The NNE was evaluated for antioxidant activities by DPPH and FRAP assays. Among the different solvent, the ethanolic extract recorded the most effective DPPH radical scavenging activity (69.2%) and FRAP value was 21.52 μm. The results of HPLC analysis revealed the presence of active principle, namely quercetin. Conclusion: It can be concluded that NNE can be used as a potent natural antioxidant to overcome oxidative stress-induced diseases.
- Subjects
EAST Indian lotus; PLANT phenols; PHENOL; TANNINS; GALLIC acid; ANTIOXIDANTS
- Publication
Drug Invention Today, 2019, Vol 11, Issue 4, p835
- ISSN
0975-7619
- Publication type
Article