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- Title
SEBORRHEIC KERATOSIS MIMICKING MALIGNANT MELANOMA: A REAL CHALLENGE. CASE REPORT AND REVIEW OF THE LITERATURE.
- Authors
Ciudin, Bianca Ionela; Ignat, Ana Sonia; Dorobantu, Dorin; Milutin, Doina; Ciucanu, Constantin Claudiu; Decean, Luminita
- Abstract
Background: Seborrheic keratosis (SK) is a common benign epidermal tumor with predominance in adult patients, showing an increasing incidence with age. Different histologic and clinical subtypes have been identified. The great variability of SK raises some difficulties in diagnosis. Dermoscopy is the most frequently used non-invasive diagnostic method to differentiate pigmented SK from other pigmented tumors, especially malignant melanoma (MM). Objective: The aim of this paper is to highlight clinical, dermoscopic and histopathological correlations in a case of SK. Materials and methods: We present the case of a 63-year-old patient attending Dermatology for an older skin lesion, who has begining to change recently, growing in size, becoming darker and irregular. Dermoscopic examination showed a scaly, hyperkeratotic surface, comedo- like openings, but also redish structureless areas and regression central area, mimicking blue-white veil, highly specific for MM. The dermoscopic score was 4,4. The excision of the lesion was performed, and the histopathological report highly expected. It came out to be a true sebborrheic keratosis, consisting of a proliferation of basaloid keratinocytes without atypia. Results: The particularity of the case is the clinical and dermoscopical resemblance of SK to MM. Conclusions: SK is the most common benign skin tumors in human, frequently treated without biopsy. Due to the clinical variability, SKs can be easily confused with MM. Dermoscopy may lead to correct diagnosis, different retrospective studies revealed 0,7-9% associated with melanomas and 48 dermoscopic features on the check list.
- Subjects
MELANOMA; KERATOSIS; BENIGN tumors; SKIN tumors; LITERATURE reviews; EPIDERMAL cyst
- Publication
Acta Medica Marisiensis, 2019, Vol 65, p42
- ISSN
2068-3324
- Publication type
Article