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- Title
The proliferation of derivative and redundant studies in endocrinology due to the application of Mendelian Randomisation and other methods to open databases.
- Authors
Tobias, Jonathan H.; Samaras, Katherine; Ivell, Richard; Davies, Terry F.; Sjöholm, Åke; Day-Haynes, Iwan; Holly, Jeff M. P.
- Abstract
The article explores the use of Mendelian Randomisation (MR) studies in endocrinology research and raises concerns about the proliferation of redundant and low-quality studies in the field. It emphasizes the need for rigorous evaluation and careful interpretation in MR studies, as well as the importance of clear justification and strong associations between genetic variants and exposures. The authors express concern about the impact of these redundant studies on the integrity of scientific literature and highlight the efforts of the journal, Frontiers in Endocrinology, to promote valuable and rigorous research.
- Subjects
ENDOCRINOLOGY
- Publication
Frontiers in Endocrinology, 2024, p1
- ISSN
1664-2392
- Publication type
Article
- DOI
10.3389/fendo.2024.1400583