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- Title
Human Immunodeficiency Virus Type 1 RNA Levels in Rectal and Seminal Compartments After Switching to Long-Acting Cabotegravir Plus Rilpivirine: A Longitudinal Study.
- Authors
Masiá, Mar; Fernández-González, Marta; Agulló, Vanesa; Mascarell, Paula; Padilla, Sergio; García-Abellán, Javier; Gutiérrez, Félix
- Abstract
Human immunodeficiency virus type 1 RNA levels were longitudinally evaluated in 211 rectal and 152 seminal samples from 12 virologically suppressed participants switching to monthly long-acting cabotegravir plus rilpivirine or continuing with daily dolutegravir-abacavir-lamivudine. Maintenance of viral suppression in rectal and seminal compartments was comparable, and blips occurred with similar frequency with both treatment regimens. Clinical Trials Registration NCT02938520.
- Subjects
SEMEN; RNA; RILPIVIRINE; ANTIRETROVIRAL agents; RECTUM; HIV; LONGITUDINAL method
- Publication
Clinical Infectious Diseases, 2023, Vol 76, Issue 3, pe748
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1093/cid/ciac676