We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Trends In Lipid Levels In Patients Admitted With Myocardial Infarction To A Regional Cardiology Centre 2000-2006.
- Authors
Scott, P.; Kodoth, V.; Noad, R.; Bennet, J.; Murphy, C.; Manoharan, G.; Adgey, A. A. J.
- Abstract
Introduction: Hypercholesterolemia is a major risk factor for coronary artery disease. Revised Joint British Society Guidelines 2005 (JBS-2) have recommended tighter lipid targets for both primary and secondary prevention. We reviewed trends in fasting lipid levels of patients admitted with Myocardial Infarction (MI) to our centre and assessed compliance with these guidelines. Methods: Fasting lipid profiles were analysed on patients admitted with an MI from January 2000 to December 2006 (n=1346). For patients admitted in 2005 lipid profile values were re-evaluated at least 6 months after admission to determine if JBS-2 target lipid values had been achieved. Results: Average Total Cholesterol decreased from 5.26 mmol/L in 2000 to 4.73 mmol/L in 2006 (p=0.026), LDL Cholesterol from 3.14 mmol/L in 2000 to 2.57 mmol/L in 2006 (p<0.001) and HDL Cholesterol rose from 1.11 mmol/L in 2000 to 1.58 mmol/L in 2002 (p=0.013) but declined to 1.33 mmol/L in 2006 (p=0.423). ST elevation Myocardial Infarction (STEMI) patients had significantly higher Total Cholesterol (5.11 Vs 4.78; p<0.001), LDL (2.97 Vs 2.69; p<0.001) and lower HDL (1.28 Vs 1.39: p=0.399) when compared with those admitted with Non ST-elevation Myocardial Infarction (NSTEMI). In 2005, 69% had achieved Total Cholesterol, 74% LDL and 71% HDL cholesterol targets 6 months after their admission. Conclusion: Our study reveals reduction in lipid profile values on admission from 2000 to 2006. We also noted that patients admitted with STEMI had a higher Total Cholesterol, LDL and lower HDL than NSTEMI. Current guidelines for primary and secondary prevention of coronary heart disease has led to more fastidious use of anti-lipid medications and has had a significant impact on the reduction of cholesterol.
- Subjects
HYPERCHOLESTEREMIA; CORONARY disease; LIPIDS; MYOCARDIAL infarction; HIGH density lipoproteins; CHOLESTEROL
- Publication
Ulster Medical Journal, 2008, Vol 77, Issue 2, p137
- ISSN
0041-6193
- Publication type
Article