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- Title
Colorectal carcinoma: is screening possible?
- Authors
Bonelli, L.
- Abstract
Colorectal cancer (CRC) is a major health problem in western countries. It is the most frequently diagnosed cancer in EU countries with about 220 000 new cases per year; the number of CRC deaths approaches 112 000. Most cancer arises from adenomatous polyps through the adenoma-carcinoma sequence; the natural history of the disease is long: the risk of invasive cancer in adenoma is about 2% per year. Given the natural history of CRC, early diagnosis represents the most appropriate tool to reduce the disease-related mortality. Several tests are available to screen healthy subjects at average risk for CRC: faecal occult blood tests, flexible sigmoidoscopy, combined faecal occult blood tests and flexible sigmoidoscopy, total colonoscopy and double contrast barium enema. Issues related to the introduction on a large scale of populationbased screening programmes for CRC are discussed.
- Subjects
EUROPEAN Union countries; COLON cancer; PUBLIC health; ADENOMA; POLYPS; BARIUM enema; COLONOSCOPY; WESTERN countries
- Publication
Techniques in Coloproctology, 2004, Vol 8, Issue s2, pS267
- ISSN
1123-6337
- Publication type
Article
- DOI
10.1007/s10151-004-0174-1