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- Title
Advances in the Treatment of Pediatric Brain Tumors.
- Authors
Kulubya, Edwin S.; Kercher, Matthew J.; Phillips, H. Westley; Antony, Reuben; Edwards, Michael S. B.
- Abstract
Pediatric brain tumors are the most common solid malignancies in children. Advances in the treatment of pediatric brain tumors have come in the form of imaging, biopsy, surgical techniques, and molecular profiling. This has led the way for targeted therapies and immunotherapy to be assessed in clinical trials for the most common types of pediatric brain tumors. Here we review the latest efforts and challenges in targeted molecular therapy, immunotherapy, and newer modalities such as laser interstitial thermal therapy.
- Subjects
GLIOMA treatment; BRAIN tumor treatment; THERAPEUTIC use of immunoglobulins; DRUG delivery systems; BIOPSY; PINEAL gland tumors; IMMUNE checkpoint inhibitors; CELLULAR therapy; PEDIATRICS; LASER therapy; DIAGNOSTIC imaging; BRAIN tumors; TERATOMA; GENE expression profiling; T cells; CANCER vaccines; IMMUNOTHERAPY; ONCOLYTIC virotherapy; CHILDREN
- Publication
Children, 2023, Vol 10, Issue 1, p62
- ISSN
2227-9067
- Publication type
Article
- DOI
10.3390/children10010062