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- Title
Birth Month and Prevalence of Atopic Dermatitis in Children Under 3 Years in Antananarivo, Madagascar.
- Authors
Sendrasoa, Fandresena Arilala; Ratovonjanahary, Volatantely Tobiniaina; Razanakoto, Naina Harinjara; Rakotoarisaona, Mendrika Fifaliana; Raharolahy, Onivola; Andrianarison, Malalaniaina; Ranaivo, Irina Mamisoa; Mbotinirina, Viviane Estelle; Sata, Moril; Ramarozatovo, Lala Soavina; Rabenja, Fahafahantsoa Rapelanoro
- Abstract
Background: Several studies have been done to evaluate the relationship between month of birth and atopic diseases but the results are contradictory. Objective: We aim to evaluate the correlation between the month of birth and the prevalence of AD in Malagasy children less than 3 years. Methods: A case-control study was conducted based on patients' data of the department of Dermatology in the University Hospital Joseph Raseta Befelatanana (UH/JRB) Antananarivo. It included 438 children less than 3 years seen in this department between January 2010 and December 2019. For each atopic dermatitis (AD) patient, two age-and sex-matched controls without a history of AD were selected from the same period. Results: This study included 146 AD cases and 292 non-AD controls. Our case-control study found that there is a statistically significant correlation between birth month and risk of AD in Malagasy children < 3 years. Compared with people born in December, people born in April had the highest risk of AD (OR: 2.11, 95% CI 0.93– 4.78), followed by people born in March (OR: 1.52, 95% CI 0.79– 2,88). Asthma, allergic rhinitis and allergic conjunctivitis were significantly correlated with AD in our patients. Conclusion: Our case-control study found that being born in April and March (dry season) may be associated with an increased risk of AD.
- Subjects
ANTANANARIVO (Madagascar); MADAGASCAR; ATOPIC dermatitis; UNIVERSITY of Colorado Hospital; ALLERGIC rhinitis; ALLERGIC conjunctivitis; ACADEMIC departments; UNIVERSITY hospitals; CASE-control method
- Publication
Journal of Asthma & Allergy, 2020, Vol 13, p265
- ISSN
1178-6965
- Publication type
Article
- DOI
10.2147/JAA.S264482