We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Detection and characterization of early gastric cancer for curative endoscopic submucosal dissection.
- Authors
Kenshi Yao; Takashi Nagahama; Toshiyuki Matsui; Akinori Iwashita
- Abstract
Because endoscopic submucosal dissection (ESD) of gastric cancer can only be curative if the cancer is detected at an early stage and a precise preoperative diagnosis is made, we reviewed the detection and characterization of early gastric cancer (EGC) using both conventional endoscopy with white-light imaging (C-WLI) and image-enhanced endoscopy (chromoendoscopy [CE] and magnifying narrow-band imaging [M-NBI]). Systematic screening of the stomach by C-WLI after ideal preparation of the patient is important for detecting a mucosal lesion, which can then be characterized using CE. However, a limitation of C-WLI with CE is the diagnosis of flat or small gastric cancers. To overcome this, M-NBI together with a comprehensive diagnostic system, termed the 'vessel plus surface classification' system, was developed and has proven very useful. Preoperative assessment for ESD involves determining: (i) histological type; (ii) size; (iii) depth of invasion; (iv) presence or absence of associated ulceration; and (v) horizontal extent of the cancer. A limitation of endoscopic diagnosis using M-NBI is the histologically undifferentiated type of carcinoma, in which case the biopsy specimen is used to make a histopathological diagnosis.
- Subjects
STOMACH cancer; ENDOSCOPY; SUBMUCOUS plexus; HISTOPATHOLOGY; CANCER treatment
- Publication
Digestive Endoscopy, 2013, Vol 25, p44
- ISSN
0915-5635
- Publication type
Article
- DOI
10.1111/den.12004