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- Title
NATURAL HISTORY OF SMALL COLORECTAL PROTUBERANT ADENOMAS.
- Authors
Hisabe, Takashi; Tsuda, Sumio; Matsui, Toshiyuki; Iwashita, Akinori
- Abstract
Most previous studies of the natural history of small colorectal adenomas showed no increase in size, no changes that would have necessitated treatment within a couple of years and that malignant transformation is rare. Using endoscopic follow up for a mean period of 43.1 months we assessed the development and progression of 408 protuberant adenomas that were under 10 mm in diameter. Of the 408 lesions, 22 (5.4%) underwent morphological changes. There were 12 lesions (2.9%) whose final tumor diameter had reached 10 mm or more. There were three lesions (0.7%) that developed and progressed into intramucosal cancer. We concluded from the literature and from our own results that small colorectal protuberant adenomas do not grow to advanced adenomas within 5 years.
- Subjects
ADENOMA; COLON cancer; TUMOR growth; ENDOSCOPY; DIAGNOSTIC imaging
- Publication
Digestive Endoscopy, 2010, Vol 22, pS43
- ISSN
0915-5635
- Publication type
Article
- DOI
10.1111/j.1443-1661.2010.00969.x