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- Title
Ovarian Function after Uterine Fibroid Embolization.
- Authors
De Lorenzo Messina, Marcos; Bozzini, Nilo; Carvalho, Ceci Mendes Lopes; Baracat, Edmund Chada
- Abstract
Purpose: The aim of this study was to evaluate the effect of uterine artery embolization (UFE) on ovarian function. Methods: Sixty (60) patients with ultrasonographic diagnosis of uterine leiomyomata were subjected to UFE with polyvinyl alcohol particles. Follicle-stimulating hormone (FSH), luteinizing hormone (LH), and estradiol (E2) levels were determined directly before, and subsequently 3 and 12 months after, the procedure between days 2 and 5 of the menstrual cycle. Results: The mean age of the participants was 43.1 years (age range, 32–51). There was no statistically significant difference in FSH, LH, and E 2 levels before and 3 and 12 months after UFE in patients with an age range of 30–44 (Group 1). FSH and LH levels were significantly increased, and E2 levels were significantly decreased, at 3 and 12 months after UFE in patients older than 45 (Group 2). Ovarian failure occurred in 19 patients (31%). Among those 19 patients, 14 (74%) developed permanent ovarian failure, and these patients were women older than 45 years. All statistical analyses were completed with the use of the Friedman test, and p-values less than 5% were considered statistically significant. Conclusions: Ovarian function may be compromised following UFE, especially in women older than 45. (J GYNECOL SURG 23:13)
- Subjects
UTERINE diseases; WOMEN'S health; FOLLICLE-stimulating hormone; OVARIAN diseases; MENSTRUAL cycle; UTERINE fibroids
- Publication
Journal of Gynecologic Surgery, 2007, Vol 23, Issue 1, p13
- ISSN
1042-4067
- Publication type
Article
- DOI
10.1089/gyn.2006.B-00251-2