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- Title
Chemical compositions and biological activities of Scutellaria pinnatifida A. Hamilt aerial parts.
- Authors
Delazar, Abbas; Nazemiyeh, Hossein; Afshar, Fariba Heshmati; Barghi, Niloofar; Esnaashari, Solmaz; Asgharian, Parina
- Abstract
Phytochemical analysis of the methanolic and dichloromethane extracts of the aerial parts of Scutellaria pinnatifida led to the isolation of a phenylpropanoid, 1-o-feruloyl-ß-D-glucose (1), two known flavonoids including luteolin-7-o-glucoside (2) and apigenin-7-o-glucoside (3), three known phenylethanoid glycosides composed of phlomisethanoside (4), syringalide A (5), and verbascoside (6), and oleic acid (7). Isolation and structural elucidation of compounds were accomplished by HPLC and spectroscopic methods (UV, 1HNMR, 13C-NMR). The extracts were also evaluated for their radical scavenging activity and insecticidal property by 2,2-diphenyl-1-picryl-hydrazyl (DPPH) assay and contact toxicity method, respectively. Among the extracts, the methanol extract showed the most potent free radical scavenging activity with a RC50 value of 0.044 ± 0.350 mg/mL which could be attributed to the presence of the isolated phenolic compounds. In the case of insecticidal activity, the n-hexane extract displayed the most potent activity and caused 10%, 15%, and 40% mortality to Oryzaephilus mercator at the concentration of 5, 10, and 15 mg/mL after 4 h of exposure.
- Subjects
CHEMICAL composition of plants; PHYTOCHEMICALS; DICHLOROMETHANE
- Publication
Research in Pharmaceutical Sciences, 2017, Vol 12, Issue 3, p187
- ISSN
1735-5362
- Publication type
Article
- DOI
10.4103/1735-5362.207199