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- Title
Folic Acid Supplementation to Prevent Neural Tube Defects: US Preventive Services Task Force Reaffirmation Recommendation Statement.
- Authors
Barry, Michael J.; Nicholson, Wanda K.; Silverstein, Michael; Chelmow, David; Coker, Tumaini Rucker; Davis, Esa M.; Donahue, Katrina E.; Jaén, Carlos Roberto; Li, Li; Ogedegbe, Gbenga; Rao, Goutham; Ruiz, John M.; Stevermer, James; Tsevat, Joel; Underwood, Sandra Millon; Wong, John B.
- Abstract
Importance: Neural tube defects are among the most common congenital malformations in the US, with an estimated 3000 pregnancies affected each year. Many of these neural tube defects are caused by low folate levels in the body. Objective: The US Preventive Services Task Force (USPSTF) commissioned a reaffirmation evidence update on the benefits and harms of folic acid supplementation. Population: Persons who are planning to or could become pregnant. Evidence Assessment: The USPSTF concludes that, for persons who are planning to or could become pregnant, there is high certainty that folic acid supplementation has a substantial net benefit to prevent neural tube defects in their offspring. Recommendation: The USPSTF recommends that all persons planning to or who could become pregnant take a daily supplement containing 0.4 to 0.8 mg (400 to 800 μg) of folic acid. (A recommendation) This 2023 Recommendation Statement from the US Preventive Services Task Force recommends that all persons planning to or who could become pregnant take a daily supplement containing 0.4 to 0.8 mg (400 to 800 μg) of folic acid (A recommendation).
- Subjects
U.S. Preventive Services Task Force; NEURAL tube defects; FOLIC acid; TASK forces; DIETARY supplements; HUMAN abnormalities
- Publication
JAMA: Journal of the American Medical Association, 2023, Vol 330, Issue 5, p454
- ISSN
0098-7484
- Publication type
Article
- DOI
10.1001/jama.2023.12876