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- Title
Multisystem Inflammatory Syndrome in Children During 3 SARS-CoV-2 Pandemic Waves in Israel.
- Authors
Jiang, Qi; Zhang, Yan Fang; Hu, Peng
- Abstract
In addition, a study[5] of blood donations in the US found that vaccine- and infection-induced SARS-CoV-2 seroprevalence increased over time and varied by age, race and ethnicity, and region. In this study,[2] the disease severity and mortality of patients who developed MIS-C after receipt of SARS-CoV-2 vaccine was lower than in a study[3] of 99 patients who developed MIS-C after SARS-CoV-2 infection, of whom 62% required vasopressors, 14% received invasive mechanical ventilation, and 2% died. This rate is substantially lower than that occurring after SARS-CoV-2 infection, estimated at approximately 200 per 1 million people.[2] Because SARS-CoV-2 infection leads to the formation of antispike and antinucleocapsid antibodies but SARS-CoV-2 vaccination does not, serological antibody testing helps distinguish the former from the latter.
- Publication
JAMA: Journal of the American Medical Association, 2022, Vol 328, Issue 15, p1561
- ISSN
0098-7484
- Publication type
Article
- DOI
10.1001/jama.2022.15217