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- Title
Improving folate (vitamin B<sub>9</sub>) stability in biofortified rice through metabolic engineering.
- Authors
Blancquaert, Dieter; Van Daele, Jeroen; Strobbe, Simon; Kiekens, Filip; Storozhenko, Sergei; De Steur, Hans; Gellynck, Xavier; Lambert, Willy; Stove, Christophe; Van Der Straeten, Dominique
- Abstract
Biofortification of staple crops could help to alleviate micronutrient deficiencies in humans. We show that folates in stored rice grains are unstable, which reduces the potential benefits of folate biofortification. We obtain folate concentrations that are up to 150 fold higher than those of wild-type rice by complexing folate to folate-binding proteins to improve folate stability, thereby enabling long-term storage of biofortified high-folate rice grains.
- Subjects
RICE; BIOFORTIFICATION; FOLIC acid; VITAMIN B complex; CELL metabolism; RICE breeding
- Publication
Nature Biotechnology, 2015, Vol 33, Issue 10, p1076
- ISSN
1087-0156
- Publication type
Article
- DOI
10.1038/nbt.3358