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- Title
Efficacy of a latency- and productive infectiondeficient Gammaherpesvirus as a vaccine strategy.
- Authors
Yong Hoon Kim; Leming Tong; Tiffany Hsu; Shih, Evan; Leang, Ronika Sitapara; Hwang, Seungmin; Sun, Ren; Wu, Ting-Ting
- Abstract
The article discusses the article "Efficacy of a latency- and productive infection-deficient Gammaherpesvirus as a vaccine strategy." It presents a hypothesis that removal of the viral genes that inhibit the host immune responses will reduce the fitness of the virus but potentially increase its immunogenicity. In this study, the authors have removed immune evasion genes from AC-RTA along with other modifications.
- Subjects
AIDS; EPSTEIN-Barr virus; HERPESVIRUSES; KAPOSI'S sarcoma; LECTURE method in teaching; VACCINES; HIGHLY active antiretroviral therapy
- Publication
Infectious Agents & Cancer, 2012, Vol 7, Issue Suppl 1, p1
- ISSN
1750-9378
- Publication type
Article
- DOI
10.1186/1750-9378-7-S1-O7