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Genome-wide association analysis of treatment resistant schizophrenia for variant discovery and polygenic assessment.
Published in:
Human Genomics, 2024, v. 18, n. 1, p. 1, doi. 10.1186/s40246-024-00673-x
By:
- Lenk, Hasan Çağın;
- Koch, Elise;
- O'Connell, Kevin S.;
- Smith, Robert Løvsletten;
- Akkouh, Ibrahim A.;
- Djurovic, Srdjan;
- Andreassen, Ole A.;
- Molden, Espen
Publication type:
Article
Developmental manifestations of polygenic risk for bipolar disorder from infancy to middle childhood.
Published in:
Translational Psychiatry, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41398-023-02522-2
By:
- Askeland, Ragna Bugge;
- Hannigan, Laurie J.;
- O'Connell, Kevin S.;
- Corfield, Elizabeth C.;
- Frei, Oleksandr;
- Thapar, Anita;
- Smith, George Davey;
- Reichborn-Kjennerud, Ted;
- Andreassen, Ole A.;
- Ask, Helga;
- Havdahl, Alexandra
Publication type:
Article
Genomic insights into the shared and distinct genetic architecture of cognitive function and schizophrenia.
Published in:
Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-66085-y
By:
- Wootton, Olivia;
- Shadrin, Alexey A.;
- Bjella, Thomas;
- Smeland, Olav B.;
- van der Meer, Dennis;
- Frei, Oleksandr;
- O'Connell, Kevin S.;
- Ueland, Torill;
- Andreassen, Ole A.;
- Stein, Dan J.;
- Dalvie, Shareefa
Publication type:
Article
Toxoplasma gondii infection associated with inflammasome activation and neuronal injury.
Published in:
Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-55887-9
By:
- Andreou, Dimitrios;
- Steen, Nils Eiel;
- Mørch-Johnsen, Lynn;
- Jørgensen, Kjetil Nordbø;
- Wortinger, Laura A.;
- Barth, Claudia;
- Szabo, Attila;
- O’Connell, Kevin S.;
- Lekva, Tove;
- Hjell, Gabriela;
- Johansen, Ingrid Torp;
- Ormerod, Monica B. E. G.;
- Haukvik, Unn K.;
- Aukrust, Pål;
- Djurovic, Srdjan;
- Yolken, Robert H.;
- Andreassen, Ole A.;
- Ueland, Thor;
- Agartz, Ingrid
Publication type:
Article
Leveraging genetic overlap between irritability and psychiatric disorders to identify genetic variants of major psychiatric disorders.
Published in:
Experimental & Molecular Medicine EMM, 2023, v. 55, n. 6, p. 1193, doi. 10.1038/s12276-023-01005-0
By:
- Jung, Kyeongmin;
- Yoon, Joohyun;
- Ahn, Yeeun;
- Kim, Soyeon;
- Shim, Injeong;
- Ko, Hyunwoong;
- Jung, Sang-Hyuk;
- Kim, Jaeyoung;
- Kim, Hyejin;
- Lee, Dong June;
- Cha, Soojin;
- Lee, Hyewon;
- Kim, Beomsu;
- Cho, Min Young;
- Cho, Hyunbin;
- Kim, Dan Say;
- Kim, Jinho;
- Park, Woong-Yang;
- Park, Tae Hwan;
- O'Connell, Kevin S.
Publication type:
Article
Shared Genetics of Multiple System Atrophy and Inflammatory Bowel Disease.
Published in:
Movement Disorders, 2021, v. 36, n. 2, p. 449, doi. 10.1002/mds.28338
By:
- Shadrin, Alexey A.;
- Mucha, Sören;
- Ellinghaus, David;
- Makarious, Mary B.;
- Blauwendraat, Cornelis;
- Sreelatha, Ashwin A.K.;
- Heras‐Garvin, Antonio;
- Ding, Jinhui;
- Hammer, Monia;
- Foubert‐Samier, Alexandra;
- Meissner, Wassilios G.;
- Rascol, Olivier;
- Pavy‐Le Traon, Anne;
- Frei, Oleksandr;
- O'Connell, Kevin S.;
- Bahrami, Shahram;
- Schreiber, Stefan;
- Lieb, Wolfgang;
- Müller‐Nurasyid, Martina;
- Schminke, Ulf
Publication type:
Article
Characterising the shared genetic determinants of bipolar disorder, schizophrenia and risk-taking.
Published in:
Translational Psychiatry, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41398-021-01576-4
By:
- Hindley, Guy;
- Bahrami, Shahram;
- Steen, Nils Eiel;
- O'Connell, Kevin S.;
- Frei, Oleksandr;
- Shadrin, Alexey;
- Bettella, Francesco;
- Rødevand, Linn;
- Fan, Chun C.;
- Dale, Anders M.;
- Djurovic, Srdjan;
- Smeland, Olav B.;
- Andreassen, Ole A.
Publication type:
Article
Extensive bidirectional genetic overlap between bipolar disorder and cardiovascular disease phenotypes.
Published in:
Translational Psychiatry, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41398-021-01527-z
By:
- Rødevand, Linn;
- Bahrami, Shahram;
- Frei, Oleksandr;
- Chu, Yunhan;
- Shadrin, Alexey;
- O'Connell, Kevin S.;
- Smeland, Olav B.;
- Elvsåshagen, Torbjørn;
- Hindley, Guy F. L.;
- Djurovic, Srdjan;
- Dale, Anders M.;
- Lagerberg, Trine V.;
- Steen, Nils Eiel;
- Andreassen, Ole A.
Publication type:
Article
Population-based body–brain mapping links brain morphology with anthropometrics and body composition.
Published in:
Translational Psychiatry, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41398-021-01414-7
By:
- Gurholt, Tiril P.;
- Kaufmann, Tobias;
- Frei, Oleksandr;
- Alnæs, Dag;
- Haukvik, Unn K.;
- van der Meer, Dennis;
- Moberget, Torgeir;
- O'Connell, Kevin S.;
- Leinhard, Olof D.;
- Linge, Jennifer;
- Simon, Rozalyn;
- Smeland, Olav B.;
- Sønderby, Ida E.;
- Winterton, Adriano;
- Steen, Nils Eiel;
- Westlye, Lars T.;
- Andreassen, Ole A.
Publication type:
Article
Effect of the NFIB rs28379954 T>C polymorphism on CYP2D6‐catalyzed metabolism of solanidine.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 2, p. 1, doi. 10.1111/cts.13743
By:
- Smith, Robert Løvsletten;
- Wollmann, Birgit M.;
- Størset, Elisabet;
- Lenk, Hasan Çağın;
- O'Connell, Kevin S.;
- Kristiansen, Marianne Kringen;
- Ingelman‐Sundberg, Magnus;
- Molden, Espen
Publication type:
Article
Impact of NFIB and CYP1A variants on clozapine serum concentration--A retrospective naturalistic cohort study on 526 patients with known smoking habits.
Published in:
CTS: Clinical & Translational Science, 2023, v. 16, n. 1, p. 62, doi. 10.1111/cts.13422
By:
- Lenk, Hasan Çağın;
- Smith, Robert Løvsletten;
- O'Connell, Kevin S.;
- Jukić, Marin M.;
- Kringen, Marianne Kristiansen;
- Andreassen, Ole A.;
- Ingelman-Sundberg, Magnus;
- Molden, Espen
Publication type:
Article
Using iPSC Models to Understand the Role of Estrogen in Neuron–Glia Interactions in Schizophrenia and Bipolar Disorder.
Published in:
Cells (2073-4409), 2021, v. 10, n. 2, p. 209, doi. 10.3390/cells10020209
By:
- Reis de Assis, Denis;
- Szabo, Attila;
- Requena Osete, Jordi;
- Puppo, Francesca;
- O'Connell, Kevin S.;
- A. Akkouh, Ibrahim;
- Hughes, Timothy;
- Frei, Evgeniia;
- A. Andreassen, Ole;
- Djurovic, Srdjan
Publication type:
Article
Rapid Metabolism Underlying Subtherapeutic Serum Levels of Atypical Antipsychotics Preceding Clozapine Treatment: A Retrospective Analysis of Real-World Data.
Published in:
CNS Drugs, 2024, v. 38, n. 6, p. 473, doi. 10.1007/s40263-024-01079-y
By:
- Lenk, Hasan Çağın;
- Smith, Robert Løvsletten;
- O'Connell, Kevin S.;
- Andreassen, Ole A.;
- Molden, Espen
Publication type:
Article
Phenotype-specific differences in polygenicity and effect size distribution across functional annotation categories revealed by AI-MiXeR.
Published in:
Bioinformatics, 2020, v. 36, n. 18, p. 4749, doi. 10.1093/bioinformatics/btaa568
By:
- Shadrin, Alexey A;
- Frei, Oleksandr;
- Smeland, Olav B;
- Bettella, Francesco;
- O'Connell, Kevin S;
- Gani, Osman;
- Bahrami, Shahram;
- Uggen, Tea K E;
- Djurovic, Srdjan;
- Holland, Dominic;
- Andreassen, Ole A;
- Dale, Anders M
Publication type:
Article
Associations Between Symptoms of Premenstrual Disorders and Polygenic Liability for Major Psychiatric Disorders.
Published in:
JAMA Psychiatry, 2023, v. 80, n. 7, p. 738, doi. 10.1001/jamapsychiatry.2023.1137
By:
- Jaholkowski, Piotr;
- Shadrin, Alexey A.;
- Jangmo, Andreas;
- Frei, Evgeniia;
- Tesfaye, Markos;
- Hindley, Guy F. L.;
- Haram, Marit;
- Rahman, Zillur;
- Athanasiu, Lavinia;
- Bakken, Nora Refsum;
- Holen, Børge;
- Fominykh, Vera;
- Kutrolli, Gleda;
- Parekh, Pravesh;
- Parker, Nadine;
- Rødevand, Linn;
- Birkenæs, Viktoria;
- Djurovic, Srdjan;
- Frei, Oleksandr;
- O'Connell, Kevin S.
Publication type:
Article
Genetic Association Between Schizophrenia and Cortical Brain Surface Area and Thickness.
Published in:
2021
By:
- Cheng, Weiqiu;
- Frei, Oleksandr;
- van der Meer, Dennis;
- Wang, Yunpeng;
- O'Connell, Kevin S.;
- Chu, Yunhan;
- Bahrami, Shahram;
- Shadrin, Alexey A.;
- Alnæs, Dag;
- Hindley, Guy F. L.;
- Lin, Aihua;
- Karadag, Naz;
- Fan, Chun-Chieh;
- Westlye, Lars T.;
- Kaufmann, Tobias;
- Molden, Espen;
- Dale, Anders M.;
- Djurovic, Srdjan;
- Smeland, Olav B.;
- Andreassen, Ole A.
Publication type:
journal article
The shared genetic basis of mood instability and psychiatric disorders: A cross‐trait genome‐wide association analysis.
Published in:
American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 2022, v. 189, n. 6, p. 207, doi. 10.1002/ajmg.b.32907
By:
- Hindley, Guy;
- O'Connell, Kevin S.;
- Rahman, Zillur;
- Frei, Oleksandr;
- Bahrami, Shahram;
- Shadrin, Alexey;
- Høegh, Margrethe C.;
- Cheng, Weiqiu;
- Karadag, Naz;
- Lin, Aihua;
- Rødevand, Linn;
- Fan, Chun C.;
- Djurovic, Srdjan;
- Lagerberg, Trine V.;
- Dale, Anders M.;
- Smeland, Olav B.;
- Andreassen, Ole A.
Publication type:
Article
Genome-wide analysis reveals genetic overlap between alcohol use behaviours, schizophrenia and bipolar disorder and identifies novel shared risk loci.
Published in:
Addiction, 2022, v. 117, n. 3, p. 600, doi. 10.1111/add.15680
By:
- Wiström, Erik D.;
- O'Connell, Kevin S.;
- Karadag, Naz;
- Bahrami, Shahram;
- Hindley, Guy F. L.;
- Aihua Lin;
- Weiqiu Cheng;
- Steen, Nils Eiel;
- Shadrin, Alexey;
- Frei, Oleksandr;
- Djurovic, Srdjan;
- Dale, Anders M.;
- Andreassen, Ole A.;
- Smeland, Olav B.
Publication type:
Article
Identification of novel genomic risk loci shared between common epilepsies and psychiatric disorders.
Published in:
Brain: A Journal of Neurology, 2023, v. 146, n. 8, p. 3392, doi. 10.1093/brain/awad038
By:
- Karadag, Naz;
- Shadrin, Alexey A;
- O'Connell, Kevin S;
- Hindley, Guy F L;
- Rahman, Zillur;
- Parker, Nadine;
- Bahrami, Shahram;
- Fominykh, Vera;
- Cheng, Weiqiu;
- Holen, Børge;
- Alvestad, Silje;
- Taubøll, Erik;
- Steen, Nils Eiel;
- Djurovic, Srdjan;
- Dale, Anders M;
- Frei, Oleksandr;
- Andreassen, Ole A;
- Smeland, Olav B
Publication type:
Article
Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools.
Published in:
2022
By:
- Bahrami, Shahram;
- Hindley, Guy;
- Winsvold, Bendik Slagsvold;
- O'Connell, Kevin S;
- Frei, Oleksandr;
- Shadrin, Alexey;
- Cheng, Weiqiu;
- Bettella, Francesco;
- Rødevand, Linn;
- Odegaard, Ketil J;
- Fan, Chun C;
- Pirinen, Matti J;
- Hautakangas, Heidi M;
- Headache, HUNT All-In;
- Dale, Anders M;
- Djurovic, Srdjan;
- Smeland, Olav B;
- Andreassen, Ole A;
- HUNT All-In Headache
Publication type:
journal article
Quantifying the Polygenic Architecture of the Human Cerebral Cortex: Extensive Genetic Overlap between Cortical Thickness and Surface Area.
Published in:
Cerebral Cortex, 2020, v. 30, n. 10, p. 5597, doi. 10.1093/cercor/bhaa146
By:
- van der Meer, Dennis;
- Frei, Oleksandr;
- Kaufmann, Tobias;
- Chen, Chi-Hua;
- Thompson, Wesley K;
- O'Connell, Kevin S;
- Sánchez, Jennifer Monereo;
- Linden, David E J;
- Westlye, Lars T;
- Dale, Anders M;
- Andreassen, Ole A
Publication type:
Article
Shared genetic loci between depression and cardiometabolic traits.
Published in:
PLoS Genetics, 2022, v. 18, n. 5, p. 1, doi. 10.1371/journal.pgen.1010161
By:
- Torgersen, Kristin;
- Rahman, Zillur;
- Bahrami, Shahram;
- Hindley, Guy Frederick Lanyon;
- Parker, Nadine;
- Frei, Oleksandr;
- Shadrin, Alexey;
- O'Connell, Kevin S.;
- Tesli, Martin;
- Smeland, Olav B.;
- Munkhaugen, John;
- Djurovic, Srdjan;
- Dammen, Toril;
- Andreassen, Ole A.
Publication type:
Article
Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10310-0
By:
- Frei, Oleksandr;
- Holland, Dominic;
- Smeland, Olav B.;
- Shadrin, Alexey A.;
- Fan, Chun Chieh;
- Maeland, Steffen;
- O'Connell, Kevin S.;
- Wang, Yunpeng;
- Djurovic, Srdjan;
- Thompson, Wesley K.;
- Andreassen, Ole A.;
- Dale, Anders M.
Publication type:
Article
Genome‐wide analyses reveal novel opioid use disorder loci and genetic overlap with schizophrenia, bipolar disorder, and major depression.
Published in:
Addiction Biology, 2023, v. 28, n. 6, p. 1, doi. 10.1111/adb.13282
By:
- Holen, Børge;
- Shadrin, Alexey A.;
- Icick, Romain;
- Filiz, Tahir T.;
- Hindley, Guy;
- Rødevand, Linn;
- O'Connell, Kevin S.;
- Hagen, Espen;
- Frei, Oleksandr;
- Bahrami, Shahram;
- Cheng, Weiqiu;
- Parker, Nadine;
- Tesfaye, Markos;
- Jahołkowski, Piotr;
- Karadag, Naz;
- Dale, Anders M.;
- Djurovic, Srdjan;
- Smeland, Olav B.;
- Andreassen, Ole A.
Publication type:
Article
Shared genetic architecture between irritable bowel syndrome and psychiatric disorders reveals molecular pathways of the gut-brain axis.
Published in:
Genome Medicine, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13073-023-01212-4
By:
- Tesfaye, Markos;
- Jaholkowski, Piotr;
- Hindley, Guy F. L.;
- Shadrin, Alexey A.;
- Rahman, Zillur;
- Bahrami, Shahram;
- Lin, Aihua;
- Holen, Børge;
- Parker, Nadine;
- Cheng, Weiqiu;
- Rødevand, Linn;
- Frei, Oleksandr;
- Djurovic, Srdjan;
- Dale, Anders M.;
- Smeland, Olav B.;
- O'Connell, Kevin S.;
- Andreassen, Ole A.
Publication type:
Article
Genome-wide Association Analysis of Schizophrenia and Vitamin D Levels Shows Shared Genetic Architecture and Identifies Novel Risk Loci.
Published in:
Schizophrenia Bulletin, 2023, v. 49, n. 6, p. 1654, doi. 10.1093/schbul/sbad063
By:
- Jaholkowski, Piotr;
- Hindley, Guy F L;
- Shadrin, Alexey A;
- Tesfaye, Markos;
- Bahrami, Shahram;
- Nerhus, Mari;
- Rahman, Zillur;
- O'Connell, Kevin S;
- Holen, Børge;
- Parker, Nadine;
- Cheng, Weiqiu;
- Lin, Aihua;
- Rødevand, Linn;
- Karadag, Naz;
- Frei, Oleksandr;
- Djurovic, Srdjan;
- Dale, Anders M;
- Smeland, Olav B;
- Andreassen, Ole A
Publication type:
Article
Shared Genetic Loci Between Schizophrenia and White Blood Cell Counts Suggest Genetically Determined Systemic Immune Abnormalities.
Published in:
Schizophrenia Bulletin, 2023, v. 49, n. 5, p. 1345, doi. 10.1093/schbul/sbad082
By:
- Steen, Nils Eiel;
- Rahman, Zillur;
- Szabo, Attila;
- Hindley, Guy F L;
- Parker, Nadine;
- Cheng, Weiqiu;
- Lin, Aihua;
- O'Connell, Kevin S;
- Sheikh, Mashhood A;
- Shadrin, Alexey;
- Bahrami, Shahram;
- Karthikeyan, Sandeep;
- Hoseth, Eva Z;
- Dale, Anders M;
- Aukrust, Pål;
- Smeland, Olav B;
- Ueland, Thor;
- Frei, Oleksandr;
- Djurovic, Srdjan;
- Andreassen, Ole A
Publication type:
Article
Elevated Systemic Levels of Markers Reflecting Intestinal Barrier Dysfunction and Inflammasome Activation Are Correlated in Severe Mental Illness.
Published in:
Schizophrenia Bulletin, 2023, v. 49, n. 3, p. 635, doi. 10.1093/schbul/sbac191
By:
- Jensen, Søren B;
- Sheikh, Mashhood A;
- Akkouh, Ibrahim A;
- Szabo, Attila;
- O'Connell, Kevin S;
- Lekva, Tove;
- Engh, John A;
- Agartz, Ingrid;
- Elvsåshagen, Torbjørn;
- Ormerod, Monica B E G;
- Weibell, Melissa A;
- Johnsen, Erik;
- Kroken, Rune A;
- Melle, Ingrid;
- Drange, Ole K;
- Nærland, Terje;
- Vaaler, Arne E;
- Westlye, Lars T;
- Aukrust, Pål;
- Djurovic, Srdjan
Publication type:
Article

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